Parieto-frontal gyrification and working memory in healthy adults.
Gyrification of the cortical mantle is a dynamic process that increases with cortical surface area and decreases with age. Increased gyrification is associated with higher scores on cognitive tasks in adults; however, the degree to which this relationship is independent of cortical surface area rema...
| Publicado en: | Brain Imaging & Behavior Vol. 12; no. 2; pp. 303 - 309 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Apr2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128837727&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 128837727 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Apr2018 vid: 12 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 128837727 128837727 NLM28290070 10.1007/s11682-017-9696-9 NLM28290070 128837727 ppf: 303 ppct: 6 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Parieto-frontal gyrification and working memory in healthy adults. aug: au: Green, Sophie Blackmon, Karen Thesen, Thomas DuBois, Jonathan Wang, Xiuyuan Halgren, Eric Devinsky, Orrin affil: Department of Neurology, Epilepsy Division, New York University School of Medicine, 10016, New York, NY, USA sug: subj: Frontal Lobe Memory, Short Term Parietal Lobe Middle Age Young Adult Male Aged Magnetic Resonance Imaging Adult Female Adolescence Scales Middle Aged: 45-64 years Aged: 65+ years Adult: 19-44 years Adolescent: 13-18 years Male Female ab: Gyrification of the cortical mantle is a dynamic process that increases with cortical surface area and decreases with age. Increased gyrification is associated with higher scores on cognitive tasks in adults; however, the degree to which this relationship is independent of cortical surface area remains undefined. This study investigates whether regional variation in gyrification is associated with domain-general and domain-specific cognition. Our hypothesis is that increased local gyrification confers a functional advantage that is independent of surface area. To quantify regional gyrification, we computed the local gyrification index (LGI) at each vertex and averaged across a bilateral parietal-frontal region associated with general intelligence and reasoning (Jung and Haier 2007). A sample of 48 healthy adults (24 males/24 females; ages 18-68 years) completed a high-resolution 3 T T1-weighted MRI and standardized administration of the Wechsler Adult Intelligence Scale (WAIS). We found a positive correlation between cortical gyrification and working memory, which remained significant after controlling for cortical surface area. Results suggest that a higher degree of local cortical folding confers a functional advantage that is independent from surface area and evident for more dynamic or "fluid" cognitive processes (i.e., working memory) rather than over-learned or "crystallized" cognitive processes. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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