Optic Disc Features in Highly Myopic Eyes: The ZOC-BHVI High Myopia Cohort Study.
Significance: Some studies reported that optic disc tilt and rotation might be risk factors for the susceptibility of high myopic eyes to develop glaucoma. However, data regarding optic disc manifestations in high myopia participants are few. It is crucial to characterize the features of optic disc...
| Publicado en: | Optometry & Vision Science Vol. 95; no. 4; pp. 318 - 323 |
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| Autores principales: | , , , , , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Apr2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128847696&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 128847696 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10405488 1X24 jtl: Optometry & Vision Science issn: 10405488 maglogo: N pubinfo: dt: Apr2018 vid: 95 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 128847696 128847696 NLM29561500 128847696 10.1097/OPX.0000000000001200 NLM29561500 128847696 ppf: 318 ppct: 5 formats: tig: atl: Optic Disc Features in Highly Myopic Eyes: The ZOC-BHVI High Myopia Cohort Study. aug: au: Zhixi Li Xinxing Guo Ou Xiao Pei Ying Lee Ran Liu Decai Wang Sankaridurg, Padmaja Mingguang He Li, Zhixi Guo, Xinxing Xiao, Ou Lee, Pei Ying Liu, Ran Wang, Decai He, Mingguang affil: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. sug: subj: Optic Nerve Abnormalities Eye Abnormalities Diagnosis Myopia Diagnosis Optic Atrophy Diagnosis Young Adult Biometrics Methods Asians Adult Male Prospective Studies Eye Abnormalities Ethnology Photography Human Refraction, Ocular China Cross Sectional Studies Myopia Ethnology Optic Atrophy Ethnology Adolescence Retina Child Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Adult: 19-44 years Adolescent: 13-18 years Child: 6-12 years Male Female ab: Significance: Some studies reported that optic disc tilt and rotation might be risk factors for the susceptibility of high myopic eyes to develop glaucoma. However, data regarding optic disc manifestations in high myopia participants are few. It is crucial to characterize the features of optic disc manifestations among high myopes.Purpose: To describe optic disc characteristics of Chinese highly myopic eyes and to investigate associated factors.Methods: This cross-sectional, observational study included 890 Chinese with bilateral high myopia (defined as ≤-6.00 diopters spherical power) in 2012. All subjects underwent cycloplegic autorefraction, ocular biometry, and fundus photography. The optic disc tilt ratio, degree of rotation, and β-zone peripapillary atrophy area were measured from the 45°optic disc-centered fundus photographs. Optic disc tilt was defined as optic disc tilt ratio, the ratio of maximum to minimum diameter of optic disc, exceeding 1.3. The definition of optic disc rotation was using optic disc rotation degree, the angle from long diameter and the vertical meridian, of >15°.Results: Among 890 participants, 2 were excluded by ungradable optic disc-centered fundus photographs. In the 888 studied right eyes, the mean spherical power was -9.36 ± 3.46 diopters with a mean axial length of 27.51 ± 1.63 mm. The proportion of optic disc tilting, rotation, and β-zone peripapillary atrophy were 81.2%, 48.3%, and 92.8%, respectively. The mean ratio of optic disc tilting and rotation degree was 1.78 ± 0.53 and 21.08 ± 19.91°; the mean area of β-zone peripapillary atrophy/optic disc head was 1.11 ± 1.22. A multiple linear regression showed that older age (P < .001), female (P = .02), and more myopic spherical equivalent (P = .005) were related to the greater optic disc tilting ratio.Conclusions: Beta-zone peripapillary atrophy, optic disc tilting, and rotation are very common in highly myopic eyes in Chinese population. Older age, female, and more myopic spherical equivalent are risk factors of higher degree of optic disc tilting. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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