Mismatch Negativity and P3a in Adolescents and Young Adults with Autism Spectrum Disorders: Behavioral Correlates and Clinical Implications.
In a sample of 37 adolescents and young adults with autism spectrum disorder (ASD) and 35 typically-developing controls (TDC), we investigated sensory symptoms by clinical measures, and Mismatch Negativity and P3a component at Fz with the frequency and duration oddball paradigms of event-related pot...
| Publicado en: | Journal of Autism & Developmental Disorders Vol. 48; no. 5; pp. 1684 - 1698 |
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| Autores principales: | , , |
| Formato: | research tables/charts tracings Journal Article |
| Publicado: |
Springer Nature
May2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=128946102&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 128946102 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01623257 AUT jtl: Journal of Autism & Developmental Disorders issn: 01623257 maglogo: N pubinfo: dt: May2018 vid: 48 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 128946102 128946102 128946102 10.1007/s10803-017-3426-4 128946102 ppf: 1684 ppct: 14 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Mismatch Negativity and P3a in Adolescents and Young Adults with Autism Spectrum Disorders: Behavioral Correlates and Clinical Implications. aug: au: Chien, Yi-Ling Hsieh, Ming Hsien Gau, Susan Shur-Fen affil: Department of Psychiatry, National Taiwan University Hospital and College of Medicine, No. 7, Chung-Shan South Road, 10002, Taipei, Taiwan sug: subj: Autism Spectrum Disorder Diagnosis Electroencephalography Autism Spectrum Disorder Diagnosis Evoked Potentials Human Sensation Avoidance Learning Attention Biological Markers Adolescence Adult Adolescent: 13-18 years Adult: 19-44 years ab: In a sample of 37 adolescents and young adults with autism spectrum disorder (ASD) and 35 typically-developing controls (TDC), we investigated sensory symptoms by clinical measures, and Mismatch Negativity and P3a component at Fz with the frequency and duration oddball paradigms of event-related potentials. Results showed that compared to TDC, ASD participants reported more sensory symptoms, and presented a shorter P3a peak latency in the duration paradigm, which was correlated with more social awareness deficits. In the frequency paradigm, P3a parameters were correlated with sensation avoiding and attention characteristics of ASD. Our findings suggest that sensory abnormality in ASD may extend into adolescence and young adulthood. P3a latency might be a potential neurophysiological marker for ASD. pubtype: Academic Journal doctype: research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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