Mean posterior corneal power and astigmatism in normal versus keratoconic eyes.
Purpose: To compare mean posterior corneal power and astigmatism in normal versus keratoconus affected eyes and determine the optimal cut-off points to maximize sensitivity and specificity in discriminating keratoconus from normal corneas. Methods: A total of 204 normal eyes and 142 keratoconus affe...
| Publicado en: | Journal of Ophthalmic & Vision Research Vol. 13; no. 2; pp. 93 - 101 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Knowledge E DMCC
Apr-Jun2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129131365&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 129131365 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20082010 AY5S jtl: Journal of Ophthalmic & Vision Research issn: 20082010 maglogo: N pubinfo: dt: Apr-Jun2018 vid: 13 iid: 2 pid: 35682 pub: Knowledge E DMCC artinfo: ui: 129131365 129131365 129131365 10.4103/jovr.jovr_19_17 129131365 ppf: 93 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Mean posterior corneal power and astigmatism in normal versus keratoconic eyes. aug: au: Feizi, Sepehr Delfazayebaher, Siamak Javadi, Mohammad Karimian, Farid Ownagh, Vahid Sadeghpour, Fatemeh affil: Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran sug: subj: Cornea Pathology Keratoconus Diagnosis Astigmatism Diagnosis Diagnosis, Eye Methods Sensitivity and Specificity Human Prospective Studies Comparative Studies Correlation Coefficient ROC Curve ab: Purpose: To compare mean posterior corneal power and astigmatism in normal versus keratoconus affected eyes and determine the optimal cut-off points to maximize sensitivity and specificity in discriminating keratoconus from normal corneas. Methods: A total of 204 normal eyes and 142 keratoconus affected eyes were enrolled in this prospective comparative study. Mean posterior corneal power and astigmatism were measured using a dual Scheimpflug camera. Correlation coefficients were calculated to assess the relationship between the magnitudes of keratometric and posterior corneal astigmatism in the study groups. Receiver operating characteristic curves were used to compare the sensitivity and specificity of the measured parameters and to identify the optimal cut-off points for discriminating keratoconus from normal corneas. Results: The mean posterior corneal power was −6.29 ± 0.20 D in the normal group and −7.77 ± 0.87 D in the keratoconus group (P < 0.001). The mean magnitudes of the posterior corneal astigmatisms were −0.32 ± 0.15 D and −0.94 ± 0.39 D in the normal and keratoconus groups, respectively (P < 0.001). Significant correlations were found between the magnitudes of keratometric and posterior corneal astigmatism in the normal (r=−0.76, P < 0.001) and keratoconus (r=−0.72, P < 0.001) groups. The mean posterior corneal power and astigmatism were highly reliable characteristics that distinguished keratoconus from normal corneas (area under the curve, 0.99 and 0.95, respectively). The optimal cut-off points of mean posterior corneal power and astigmatism were −6.70 D and −0.54 D, respectively. Conclusion: Mean posterior corneal power and astigmatism measured using a Galilei analyzer camera might have potential in diagnosing keratoconus. The cut-off points provided can be used for keratoconus screening. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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