Intravitreal injection of anti-vascular endothelial growth factor agents for ocular vascular diseases: Clinical practice guideline.

Purpose: To provide the clinical recommendations for the administration of intravitreal anti-vascular endothelial growth factor (VEGF) drugs especially bavacizumab for ocular vascular diseases including diabetic macular edema, neovascular age-related macular degeneration, myopic choroidal neovascula...

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Publicado en:Journal of Ophthalmic & Vision Research Vol. 13; no. 2; pp. 158 - 170
Autores principales: Nikkhah, Homayoun, Karimi, Saeed, Ahmadieh, Hamid, Azarmina, Mohsen, Abrishami, Majid, Ahoor, Hossein, Alizadeh, Yousef, Behboudi, Hasan, Daftarian, Narsis, Dehghan, Mohammad, Entezari, Morteza, Farrahi, Fereydoun, Ghanbari, Heshmatollah, Falavarjani, Khalil, Javadi, Mohammad, Karkhaneh, Reza, Moradian, Siamak, Manaviat, Masoud, Mehryar, Morsal, Nourinia, Ramin
Formato: practice guidelines tables/charts Journal Article
Publicado: Knowledge E DMCC Apr-Jun2018
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Intravitreal injection of anti-vascular endothelial growth factor agents for ocular vascular diseases: Clinical practice guideline.
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          Nikkhah, Homayoun
          Karimi, Saeed
          Ahmadieh, Hamid
          Azarmina, Mohsen
          Abrishami, Majid
          Ahoor, Hossein
          Alizadeh, Yousef
          Behboudi, Hasan
          Daftarian, Narsis
          Dehghan, Mohammad
          Entezari, Morteza
          Farrahi, Fereydoun
          Ghanbari, Heshmatollah
          Falavarjani, Khalil
          Javadi, Mohammad
          Karkhaneh, Reza
          Moradian, Siamak
          Manaviat, Masoud
          Mehryar, Morsal
          Nourinia, Ramin
        affil: Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran
      sug:
        subj:
          Bevacizumab Administration and Dosage
          Administration, Intraocular
          Eye Diseases Drug Therapy
          Vascular Diseases Drug Therapy
          Macular Degeneration Drug Therapy
          Neovascularization, Pathologic Drug Therapy
          Retinal Vein Occlusion Drug Therapy
          Retinal Diseases Drug Therapy
          Diabetic Retinopathy Drug Therapy
          Bevacizumab Therapeutic Use
          Vascular Endothelial Growth Factors
          Decision Making, Clinical
          Medical Practice, Evidence-Based
          Policy Making
          Injections
          Eye Care
      ab: Purpose: To provide the clinical recommendations for the administration of intravitreal anti-vascular endothelial growth factor (VEGF) drugs especially bavacizumab for ocular vascular diseases including diabetic macular edema, neovascular age-related macular degeneration, myopic choroidal neovascularization, retinal vein occlusion and central serous chorioretinopathy. Methods: Twenty clinical questions were developed by the guideline technical committee. Relevant websites and databases were searched to find out the pertinent clinical practice guidelines to answer the questions. The technical committee provided possible answers (scenarios) according to the available evidences for each question. All scenarios along with their levels of evidence and the supported articles were sent to the experts for external review. If the experts did not agree on any of the scenarios for one particular clinical question, the technical committee reviewed all scenarios and their pertinent evidences and made the necessary decision. After that, the experts were asked to score them again. All confirmed scenarios were gathered as the final recommendations. Results: All the experts agreed on at least one of the scenarios. The technical committee extracted the agreed scenario for each clinical question as the final recommendation. Finally, 56 recommendations were developed for the procedure of intravitreal anti-VEGF injection and their applications in the management of ocular vascular diseases. Conclusion: The implementation of this guideline can standardize the management of the common ocular vascular diseases by intravitreal injection of anti-VEGF agents. It can lead to better policy-making and evidence-based clinical decision by ophthalmologists and optimal evidence based eye care for patients.
      pubtype: Academic Journal
      doctype:
        practice guidelines
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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