Development and validation of a simplified algorithm for neonatal gestational age assessment - protocol for the Alliance for Maternal Newborn Health Improvement (AMANHI) prospective cohort study.
Objective: The objective of the Alliance for Maternal and Newborn Health Improvement (AMANHI) gestational age study is to develop and validate a programmatically feasible and simple approach to accurately assess gestational age of babies after they are born. The study will provide accurate, populati...
| Publicado en: | Journal of Global Health Vol. 7; no. 2; pp. 496 - 507 |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Edinburgh University Global Health Society
Dec2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129284736&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 129284736 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20472978 DBQG jtl: Journal of Global Health issn: 20472978 maglogo: N pubinfo: dt: Dec2017 vid: 7 iid: 2 pid: 72708 pub: Edinburgh University Global Health Society artinfo: ui: 129284736 129284736 NLM29163937 129284736 10.7189/jogh.07.021201 NLM29163937 129284736 ppf: 496 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Development and validation of a simplified algorithm for neonatal gestational age assessment - protocol for the Alliance for Maternal Newborn Health Improvement (AMANHI) prospective cohort study. aug: au: Baqui, Abdullah Ahmed, Parvez Dasgupta, Sushil Kanta Begum, Nazma Rahman, Mahmoodur Islam, Nasreen Quaiyum, Mohammad Kirkwood, Betty Edmond, Karen Shannon, Caitlin Newton, Samuel Hurt, Lisa Jehan, Fyezah Nisar, Imran Hussain, Atiya Nadeem, Naila Ilyas, Muhammad Zaidi, Anita Sazawal, Sunil Deb, Saikat affil: AMANHI Gestational Age Study Group, Bangladesh (Sylhet) sug: subj: Gestational Age Neonatal Assessment Methods Algorithms Asia Infant Mortality Infant Pregnancy Human Reproducibility of Results Prospective Studies Infant, Newborn Africa South of the Sahara Risk Assessment Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Funding Source Infant: 1-23 months Infant, Newborn: birth-1 month Female ab: Objective: The objective of the Alliance for Maternal and Newborn Health Improvement (AMANHI) gestational age study is to develop and validate a programmatically feasible and simple approach to accurately assess gestational age of babies after they are born. The study will provide accurate, population-based rates of preterm birth in different settings and quantify the risks of neonatal mortality and morbidity by gestational age and birth weight in five South Asian and sub-Saharan African sites.Methods: This study used on-going population-based cohort studies to recruit pregnant women early in pregnancy (<20 weeks) for a dating ultrasound scan. Implementation is harmonised across sites in Ghana, Tanzania, Zambia, Bangladesh and Pakistan with uniform protocols and standard operating procedures. Women whose pregnancies are confirmed to be between 8 to 19 completed weeks of gestation are enrolled into the study. These women are followed up to collect socio-demographic and morbidity data during the pregnancy. When they deliver, trained research assistants visit women within 72 hours to assess the baby for gestational maturity. They assess for neuromuscular and physical characteristics selected from the Ballard and Dubowitz maturation assessment scales. They also measure newborn anthropometry and assess feeding maturity of the babies. Computer machine learning techniques will be used to identify the most parsimonious group of signs that correctly predict gestational age compared to the early ultrasound date (the gold standard). This gestational age will be used to categorize babies into term, late preterm and early preterm groups. Further, the ultrasound-based gestational age will be used to calculate population-based rates of preterm birth.Importance Of the Study: The AMANHI gestational age study will make substantial contribution to improve identification of preterm babies by frontline health workers in low- and middle- income countries using simple evaluations. The study will provide accurate preterm birth estimates. This new information will be crucial to planning and delivery of interventions for improving preterm birth outcomes, particularly in South Asia and sub-Saharan Africa. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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