Heart Rate and Oxygen Saturation Change Patterns During 6-min Walk Test in Subjects With Chronic Thromboembolic Pulmonary Hypertension.

BACKGROUND: The 6-min walk test (6MWT) is commonly performed to assess functional status in patients with chronic thromboembolic pulmonary hypertension. However, changes in heart rate and oxygen saturation (...) patterns during 6MWT in patients with chronic thromboembolic pulmonary hypertension rema...

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Publicado en:Respiratory Care Vol. 63; no. 5; pp. 573 - 584
Autores principales: Takeshi Inagaki, Jiro Terada, Misuzu Yahaba, Naoko Kawata, Takayuki Jujo, Kengo Nagashima, Seiichiro Sakao, Nobuhiro Tanabe, Koichiro Tatsumi
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. May2018
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        atl: Heart Rate and Oxygen Saturation Change Patterns During 6-min Walk Test in Subjects With Chronic Thromboembolic Pulmonary Hypertension.
      aug:
        au:
          Takeshi Inagaki
          Jiro Terada
          Misuzu Yahaba
          Naoko Kawata
          Takayuki Jujo
          Kengo Nagashima
          Seiichiro Sakao
          Nobuhiro Tanabe
          Koichiro Tatsumi
        affil: Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan
      sug:
        subj:
          Pulmonary Arterial Hypertension Diagnosis
          Thromboembolism
          Walking Speed
          Heart Rate Evaluation
          Human
          Oxygen Saturation
          Chronic Disease
          Patient Assessment
          Patient Selection
          Multivariate Analysis
          Hemodynamics
          Disease Progression
          Retrospective Design
          Descriptive Statistics
          Male
          Female
          Middle Age
          Middle Aged: 45-64 years
          Male
          Female
      ab: BACKGROUND: The 6-min walk test (6MWT) is commonly performed to assess functional status in patients with chronic thromboembolic pulmonary hypertension. However, changes in heart rate and oxygen saturation (...) patterns during 6MWT in patients with chronic thromboembolic pulmonary hypertension remain unclear. METHODS: Thirty-one subjects with chronic thromboembolic pulmonary hypertension were retrospectively evaluated to examine the relationships between the change in heart rate (Δheart rate), heart rate acceleration time, slope of heart rate acceleration, heart rate recovery during the first minute after 6MWT (HRR1), change in ... (Δ...), ... reduction time, and ... recovery time during 6MWT, and the severity of pulmonary hemodynamics assessed by right heart catheterization and echocardiography. RESULTS: Subjects with severe chronic thromboembolic pulmonary hypertension had significantly longer heart rate acceleration time (144.9 ± 63.9 s vs 96.0 ± 42.5 s, P = .033), lower Δheart rate (47.4 ± 16.9 vs 61.8 ± 13.6 beats, P = .02), and lower HRR1 (13.3 ± 9.0 beats vs 27.1 ± 9.2 beats, P < .001) compared to subjects with mild chronic thromboembolic pulmonary hypertension. Subjects with severe chronic thromboembolic pulmonary hypertension also had significantly longer ... reduction time (178.3 ± 70.3 s vs 134.3 ± 58.4 s, P = .03) and ... recovery time (107.6 ± 35.3 s vs 69.8 ± 32.7 s, P = .004) than did subjects with mild chronic thromboembolic pulmonary hypertension. Multivariate linear regression analysis showed only mean pulmonary arterial pressure independently was associated with heart rate acceleration time and slope of heart rate acceleration. CONCLUSIONS: Heart rate and ... change patterns during 6MWT are predominantly associated with pulmonary hemodynamics in subjects with chronic thromboembolic pulmonary hypertension. Evaluating heart rate and ... change patterns during 6MWT may serve as a safe and convenient way to follow the change in pulmonary hemodynamics.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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