Obesity-related metabolic and endocrine disorders diagnosed during postoperative follow-up of slipped capital femoral epiphysis.

Background and purpose — Patients with slipped capital femoral epiphysis (SCFE) are phenotypically overweight or obese and may therefore require clinical follow-up of obesity-related disorders. We evaluated obesity-related disorders such as dyslipidemia, type 2 diabetes mellitus (DM), and vitamin-D...

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Publicado en:Acta Orthopaedica Vol. 89; no. 3; pp. 314 - 320
Autores principales: Ucpunar, Hanifi, Camurcu, Ismet Yalkin, Duman, Serda, Ucpunar, Esra, Sofu, Hakan, Bayhan, Avni Ilhan
Formato: research tables/charts Journal Article
Publicado: Medical Journals Sweden AB Jun2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2018
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      pub: Medical Journals Sweden AB
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        10.1080/17453674.2018.1445167
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        atl: Obesity-related metabolic and endocrine disorders diagnosed during postoperative follow-up of slipped capital femoral epiphysis.
      aug:
        au:
          Ucpunar, Hanifi
          Camurcu, Ismet Yalkin
          Duman, Serda
          Ucpunar, Esra
          Sofu, Hakan
          Bayhan, Avni Ilhan
        affil: Erzincan University Faculty of Medicine, Department of Orthopaedics and Traumatology
      sug:
        subj:
          Obesity
          Postoperative Period
          Epiphyses, Slipped Surgery
          Hyperlipidemia Diagnosis
          Diabetes Mellitus, Type 2 Diagnosis
          Vitamin D Deficiency Diagnosis
          Orthopedic Surgery Methods
          Human
          After Care
          Adolescence
          Retrospective Design
          Body Mass Index
          Lipids Blood
          Lipoproteins, LDL Cholesterol Blood
          Lipoproteins, HDL Cholesterol Blood
          Triglycerides Blood
          Fasting
          Blood Glucose
          Glycated Hemoglobin Blood
          Vitamin D Blood
          Diabetes Mellitus, Type 2 Risk Factors
          Epiphyses, Slipped Diagnosis
          Cholesterol Blood
          Adolescent: 13-18 years
      ab: Background and purpose — Patients with slipped capital femoral epiphysis (SCFE) are phenotypically overweight or obese and may therefore require clinical follow-up of obesity-related disorders. We evaluated obesity-related disorders such as dyslipidemia, type 2 diabetes mellitus (DM), and vitamin-D deficiency during the postoperative period in patients with SCFE. Patients and methods — 51 patients who were operated and followed-up for SCFE and 62 healthy adolescents without SCFE (control group) were included in this retrospective study. Patients’ BMI, serum lipid profile (total cholesterol, LDL-C, HDL-C, triglyceride), fasting blood glucose, HbA1c, and serum vitamin D levels were evaluated. Results — At the time of surgery, 45 patients in the SCFE group were overweight or obese (BMI >25). At the latest follow-up, 42 patients in the SCFE group and 53 patients in the control group were overweight/obese. Abnormal serum lipid profile and ratio of total dyslipidemia were similar between the groups. 8 patients had abnormal HbA1c levels in the SCFE group and mean HbA1c levels were significantly higher in the SCFE group (p = 0.03). All patients and controls had low levels of vitamin D. Interpretation — Although serum lipid profile and vitamin D levels were detected as similar in SCFE and control groups, the potential risk of type 2 DM identified via abnormal HbA1c levels was significantly higher in patients with SCFE. We recommend that patients diagnosed with SCFE should be considered as potential candidates for type 2 DM; thus follow-up after surgical treatment should include not only orthopedic outcomes but also evaluation of future risk for DM.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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