Discrimination surfaces with application to region-specific brain asymmetry analysis.
Discrimination surfaces are here introduced as a diagnostic tool for localizing brain regions where discrimination between diseased and nondiseased participants is higher. To estimate discrimination surfaces, we introduce a Mann-Whitney type of statistic for random fields and present large-sample re...
| Publicado en: | Statistics in Medicine Vol. 37; no. 11; pp. 1859 - 1874 |
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| Autores principales: | , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
5/20/2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129492585&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 129492585 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02776715 2DZ jtl: Statistics in Medicine issn: 02776715 maglogo: Y pubinfo: dt: 5/20/2018 vid: 37 iid: 11 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 129492585 129492585 NLM29508421 129492585 10.1002/sim.7611 NLM29508421 129492585 ppf: 1859 ppct: 15 formats: tig: atl: Discrimination surfaces with application to region-specific brain asymmetry analysis. aug: au: Martos, Gabriel de Carvalho, Miguel affil: Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires‐CONICET, Buenos Aires, Argentina sug: subj: Brain Pathology Brain Models, Statistical Schizophrenia Imaging, Three-Dimensional Statistics and Numerical Data Image Interpretation, Computer Assisted Statistics and Numerical Data Schizophrenia Pathology Magnetic Resonance Imaging Statistics and Numerical Data ROC Curve Pharmacokinetics Brain Diseases Computer Simulation Systems Analysis Statistics Brain Diseases Pathology Human Validation Studies Comparative Studies Evaluation Research Multicenter Studies ab: Discrimination surfaces are here introduced as a diagnostic tool for localizing brain regions where discrimination between diseased and nondiseased participants is higher. To estimate discrimination surfaces, we introduce a Mann-Whitney type of statistic for random fields and present large-sample results characterizing its asymptotic behavior. Simulation results demonstrate that our estimator accurately recovers the true surface and corresponding interval of maximal discrimination. The empirical analysis suggests that in the anterior region of the brain, schizophrenic patients tend to present lower local asymmetry scores in comparison with participants in the control group. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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