Population pharmacokinetics and pharmacodynamics of ticagrelor and AR-C124910XX in Chinese healthy male subjects.

Background: Ticagrelor, the first reversible P2Y12 receptor antagonist, exhibits faster onset and offset of antiplatelet effects and more consistent platelet inhibition than clopidogrel in both healthy subjects and patients with stable coronary artery disease.Objective: The objectives of this study...

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Detalles Bibliográficos
Publicado en:European Journal of Clinical Pharmacology Vol. 74; no. 6; pp. 745 - 755
Autores principales: Liu, Shuaibing, Xue, Ling, Shi, Xiangfen, Sun, Zhiyong, Zhu, Zhenfeng, Zhang, Xiaojian, Tian, Xin
Formato: equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Jun2018
Acceso en línea:Ver este registro en EBSCOhost