MRI/US fusion-guided prostate biopsy allows for equivalent cancer detection with significantly fewer needle cores in biopsy-naive men.
Purpose: We aimed to investigate the efficiency and cancer detection of magnetic resonance imaging (MRI) / ultrasonography (US) fusion-guided prostate biopsy in a cohort of biopsy-naive men compared with standard-of-care systematic extended sextant transrectal ultrasonography (TRUS)-guided biopsy.Me...
| Publicado en: | Diagnostic & Interventional Radiology Vol. 24; no. 3; pp. 115 - 121 |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Galenos Yayinevi Tic. LTD. STI
May/Jun2018
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129561582&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 129561582 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13053825 39NM jtl: Diagnostic & Interventional Radiology issn: 13053825 maglogo: N pubinfo: dt: May/Jun2018 vid: 24 iid: 3 pid: 28155 pub: Galenos Yayinevi Tic. LTD. STI artinfo: ui: 129561582 129561582 NLM29770762 129561582 10.5152/dir.2018.17422 NLM29770762 129561582 ppf: 115 ppct: 6 formats: fmt: @attributes: type: P tig: atl: MRI/US fusion-guided prostate biopsy allows for equivalent cancer detection with significantly fewer needle cores in biopsy-naive men. aug: au: Yarlagadda, Vidhush K. Win Shun Lai Gordetsky, Jennifer B. Porter, Kristin K. Nix, Jeffrey W. Thomas, John V. Rais-Bahrami, Soroush Lai, Win Shun affil: Department of Urology University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA sug: subj: Ultrasonography Methods Magnetic Resonance Imaging Methods Prostate Pathology Prostatic Neoplasms Pathology Biopsy Equipment and Supplies Human Male Prostatic Neoplasms Aged Middle Age Biopsy, Needle Methods Prostate Metabolism Ultrasonic Therapy Methods Prostate-Specific Antigen Blood Biopsy Methods Prospective Studies Retrospective Design Validation Studies Comparative Studies Evaluation Research Multicenter Studies Aged: 65+ years Middle Aged: 45-64 years Male ab: Purpose: We aimed to investigate the efficiency and cancer detection of magnetic resonance imaging (MRI) / ultrasonography (US) fusion-guided prostate biopsy in a cohort of biopsy-naive men compared with standard-of-care systematic extended sextant transrectal ultrasonography (TRUS)-guided biopsy.Methods: From 2014 to 2016, 72 biopsy-naive men referred for initial prostate cancer evaluation who underwent MRI of the prostate were prospectively evaluated. Retrospective review was performed on 69 patients with lesions suspicious for malignancy who underwent MRI/US fusion-guided biopsy in addition to systematic extended sextant biopsy. Biometric, imaging, and pathology data from both the MRI-targeted biopsies and systematic biopsies were analyzed and compared.Results: There were no significant differences in overall prostate cancer detection when comparing MRI-targeted biopsies to standard systematic biopsies (P = 0.39). Furthermore, there were no significant differences in the distribution of severity of cancers based on grade groups in cases with cancer detection (P = 0.68). However, significantly fewer needle cores were taken during the MRI/US fusion-guided biopsy compared with systematic biopsy (63% less cores sampled, P < 0.001) CONCLUSION: In biopsy-naive men, MRI/US fusion-guided prostate biopsy offers equal prostate cancer detection compared with systematic TRUS-guided biopsy with significantly fewer tissue cores using the targeted technique. This approach can potentially reduce morbidity in the future if used instead of systematic biopsy without sacrificing the ability to detect prostate cancer, particularly in cases with higher grade disease. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|