Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis.

Background: The RhoA activating protein Net1 contributes to breast cancer cell proliferation, motility, and invasion in vitro, yet little is known about its roles in mammary gland tumorigenesis and metastasis.Methods: Net1 knockout (KO) mice were bred to mice with mammary gland specific expression o...

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Detalles Bibliográficos
Publicado en:Breast Cancer Research Vol. 20; no. 1
Autores principales: Zuo, Yan, Ulu, Arzu, Chang, Jeffrey T., Frost, Jeffrey A.
Formato: research Journal Article
Publicado: BioMed Central 5/16/2018
Acceso en línea:Ver este registro en EBSCOhost