Kinematic Features of Jaw and Lips Distinguish Symptomatic From Presymptomatic Stages of Bulbar Decline in Amyotrophic Lateral Sclerosis.

Purpose: The goals of this study were to (a) classify speech movements of patients with amyotrophic lateral sclerosis (ALS) in presymptomatic and symptomatic phases of bulbar function decline relying solely on kinematic features of lips and jaw and (b) identify the most important measures that detec...

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Publicado en:Journal of Speech, Language & Hearing Research Vol. 61; no. 5; pp. 1118 - 1130
Autores principales: Bandini, Andrea, Green, Jordan R., Jun Wang, Campbell, Thomas F., Zinman, Lorne, Yunusova, Yana
Formato: Artículo
Publicado: American Speech-Language-Hearing Association May2018
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2018
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      pub: American Speech-Language-Hearing Association
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        10.1044/2018_JSLHR-S-17-0262
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        atl: Kinematic Features of Jaw and Lips Distinguish Symptomatic From Presymptomatic Stages of Bulbar Decline in Amyotrophic Lateral Sclerosis.
      aug:
        au:
          Bandini, Andrea
          Green, Jordan R.
          Jun Wang
          Campbell, Thomas F.
          Zinman, Lorne
          Yunusova, Yana
        affil:
          University Health Network, Toronto Rehabilitation Institute, Ontario, Canada
          Department of Communication Sciences and Disorders, MGH Institute of Health Professions, Boston, MA
          Department of Bioengineering, The University of Texas at Dallas, Richardson
          Callier Center for Communication Disorders, The University of Texas at Dallas
          Neurology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
          Brain Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
          Department of Speech-Language Pathology, University of Toronto, Ontario, Canada
      su:
        Progressive bulbar palsy
        Amyotrophic lateral sclerosis
        Algorithms
        Jaws
        Kinematics
        Lips
        Intelligibility of speech
      sug:
        subj:
          Progressive bulbar palsy
          Amyotrophic lateral sclerosis
          Algorithms
          Jaws
          Kinematics
          Lips
          Intelligibility of speech
      ab: Purpose: The goals of this study were to (a) classify speech movements of patients with amyotrophic lateral sclerosis (ALS) in presymptomatic and symptomatic phases of bulbar function decline relying solely on kinematic features of lips and jaw and (b) identify the most important measures that detect the transition between early and late bulbar changes. Method: One hundred ninety-two recordings obtained from 64 patients with ALS were considered for the analysis. Feature selection and classification algorithms were used to analyze lip and jaw movements recorded with Optotrak Certus (Northern Digital Inc.) during a sentence task. A feature set, which included 35 measures of movement range, velocity, acceleration, jerk, and area measures of lips and jaw, was used to classify sessions according to the speaking rate into presymptomatic (> 160 words per minute) and symptomatic (< 160 words per minute) groups. Results: Presymptomatic and symptomatic phases of bulbar decline were distinguished with high accuracy (87%), relying only on lip and jaw movements. The best features that allowed detecting the differences between early and later bulbar stages included cumulative path of lower lip and jaw, peak values of velocity, acceleration, and jerk of lower lip and jaw. Conclusion: The results established a relationship between facial kinematics and bulbar function decline in ALS. Considering that facial movements can be recorded by means of novel inexpensive and easy-to-use, videobased methods, this work supports the development of an automatic system for facial movement analysis to help clinicians in tracking the disease progression in ALS.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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