Mortality prediction system for heart failure with orthogonal relief and dynamic radius means.

Objective: This paper constructs a mortality prediction system based on a real-world dataset. This mortality prediction system aims to predict mortality in heart failure (HF) patients. Effective mortality prediction can improve resources allocation and clinical outcomes, avoiding inappropriate overt...

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Publicado en:International Journal of Medical Informatics Vol. 115; pp. 10 - 18
Autores principales: Wang, Zhe, Yao, Lijuan, Li, Dongdong, Ruan, Tong, Liu, Min, Gao, Ju
Formato: research Journal Article
Publicado: Elsevier B.V. Jul2018
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: International Journal of Medical Informatics
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      dt: Jul2018
      vid: 115
      pid: 467
      pub: Elsevier B.V.
      place: New York, New York
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        129683426
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        NLM29779711
        129683426
        10.1016/j.ijmedinf.2018.04.003
        NLM29779711
        129683426
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        atl: Mortality prediction system for heart failure with orthogonal relief and dynamic radius means.
      aug:
        au:
          Wang, Zhe
          Yao, Lijuan
          Li, Dongdong
          Ruan, Tong
          Liu, Min
          Gao, Ju
        affil: Key Laboratory of Advanced Control and Optimization for Chemical Processes, Ministry of Education, East China University of Science and Technology, Shanghai, 200237, China
      sug:
        subj:
          Heart Failure Mortality
          Models, Statistical
          Human
          Algorithms
          Hospital Mortality
          Aged
          Female
          Heart Failure Therapy
          China
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Arthritis Impact Measurement Scales
          Scales
          Aged: 65+ years
          Female
      ab: Objective: This paper constructs a mortality prediction system based on a real-world dataset. This mortality prediction system aims to predict mortality in heart failure (HF) patients. Effective mortality prediction can improve resources allocation and clinical outcomes, avoiding inappropriate overtreatment of low-mortality patients and discharging of high-mortality patients. This system covers three mortality prediction targets: prediction of in-hospital mortality, prediction of 30-day mortality and prediction of 1-year mortality.Materials and Methods: HF data are collected from the Shanghai Shuguang hospital. 10,203 in-patients records are extracted from encounters occurring between March 2009 and April 2016. The records involve 4682 patients, including 539 death cases. A feature selection method called Orthogonal Relief (OR) algorithm is first used to reduce the dimensionality. Then, a classification algorithm named Dynamic Radius Means (DRM) is proposed to predict the mortality in HF patients.Results and Discussions: The comparative experimental results demonstrate that mortality prediction system achieves high performance in all targets by DRM. It is noteworthy that the performance of in-hospital mortality prediction achieves 87.3% in AUC (35.07% improvement). Moreover, the AUC of 30-day and 1-year mortality prediction reach to 88.45% and 84.84%, respectively. Especially, the system could keep itself effective and not deteriorate when the dimension of samples is sharply reduced.Conclusions: The proposed system with its own method DRM can predict mortality in HF patients and achieve high performance in all three mortality targets. Furthermore, effective feature selection strategy can boost the system. This system shows its importance in real-world applications, assisting clinicians in HF treatment by providing crucial decision information.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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