Relation between Mitral Annular Plane Systolic Excursion and Global longitudinal strain in normal subjects: The HUNT study.

Background: Left ventricular (LV) systolic long‐axis shortening can be measured as Mitral Annular Plane Systolic Excursion (MAPSE). Global longitudinal strain (GLS) is relative LV shortening, equivalent to normalizing MAPSE for LV length (MAPSEn). The objective of this study was to test whether norm...

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Publicado en:Echocardiography Vol. 35; no. 5; pp. 603 - 611
Autores principales: Støylen, Asbjørn, Mølmen, Harald E., Dalen, Håvard
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell May2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2018
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/echo.13825
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        atl: Relation between Mitral Annular Plane Systolic Excursion and Global longitudinal strain in normal subjects: The HUNT study.
      aug:
        au:
          Støylen, Asbjørn
          Mølmen, Harald E.
          Dalen, Håvard
        affil: Faculty of medicine, Department of Medical Imaging and Circulation, Norwegian University of Science and Technology, Trondheim, Norway
      sug:
        subj:
          Ventricular Dysfunction, Left Ultrasonography
          Echocardiography Methods
          Ventricular Function, Left
          Body Surface Area
          Reference Values
          Heart Anatomy and Histology
          Human
          Sex Factors
          Age Factors
          Descriptive Statistics
          Bias (Research)
      ab: Background: Left ventricular (LV) systolic long‐axis shortening can be measured as Mitral Annular Plane Systolic Excursion (MAPSE). Global longitudinal strain (GLS) is relative LV shortening, equivalent to normalizing MAPSE for LV length (MAPSEn). The objective of this study was to test whether normalizing LV shortening reduced biological variability of MAPSE due to normalizing for heart size and, possibly BSA. Secondly to provide normal reference values for MAPSE. Methods and results: A total of 1266 subjects from the Nord‐Trøndelag Health Study (HUNT), without evidence of heart disease were examined. MAPSE and wall lengths were measured in all three standard apical views, while GLS has been published previously. Mean MAPSE was 1.58 (0.25) cm, MAPSEn 16.3 (2.4)%, and GLS 16.7 (2.4)%. All measures declined with age, correlations between ‐0.50 and −0.41. MAPSE was gender independent, and less BSA dependent than MAPSEn and GLS, while relative standard deviations (SDs) were similar for all three measures. Conclusions: MAPSE, MAPSEn, and GLS have similar biological variability, which is mainly due to age variation, indicating they are equivalent in normal, and normalizing for BSA will not reduce the variability. Normalizing MAPSE for LV length (MAPSEn and GLS) normalizes for one dimension only, inducing a systematic error, which increases BSA and gender dependence. Normal age‐related, gender‐independent values for MAPSE are provided.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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