Endogenous Cryptococcal Endophthalmitis in Immunocompetent Host: Case Report and Review of Multimodal Imaging Findings and Treatment.

Purpose: To describe a case of bilateral endogenous cryptococcal endophthalmitis in an immunocompetent host and to review adjunctive ophthalmic imaging patterns and treatment.Methods: A retrospective case report.Results: A 45-year-old female patient with two distinct presentations of endogenous cryp...

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Detalles Bibliográficos
Publicado en:Ocular Immunology & Inflammation Vol. 26; no. 4; pp. 518 - 523
Autores principales: Amphornphruet, Atchara, Silpa-archa, Sukhum, Preble, Janine M., Foster, C. Stephen
Formato: case study review Journal Article
Publicado: Taylor & Francis Ltd 2018
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Purpose: To describe a case of bilateral endogenous cryptococcal endophthalmitis in an immunocompetent host and to review adjunctive ophthalmic imaging patterns and treatment.Methods: A retrospective case report.Results: A 45-year-old female patient with two distinct presentations of endogenous cryptococcal endophthalmitis in each eye presented initially with progressive blurred vision in the left eye, beginning more than 10 years after a craniotomy with ventriculoperitoneal shunt. Complete ophthalmic imaging was conducted and compared with data from previous literature. Administration of amphotericin-B had poorly responded; however, consolidation of fluconazole resulted in disease stabilization.Conclusions: Bilateral intraocular cryptococcal infection can present with two distinct patterns of posterior segment findings. A review of ophthalmic imaging patterns found consistency in some characteristics of A-scan ultrasonogram and fundus fluorescein angiogram. Besides conventional treatment, voriconazole is likely to play an important role in the management of cryptococcal endophthalmitis.