Application of Viable Cryopreserved Human Placental Membrane Grafts in the Treatment of Wounds of Diverse Etiologies: A Case Series.
There is evidence in the literature that viable cryopreserved human placental membrane (vCHPM) grafts are effective in treating diabetic foot ulcers and venous leg ulcers. Objective. This case series presents 3 cases of chronic ulcerations -- 1 arterial ulcer (AU), 1 pressure ulcer (PU), and 1 recur...
| Publicado en: | Wounds: A Compendium of Clinical Research & Practice Vol. 30; no. 3; pp. 57 - 62 |
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| Autores principales: | , , , |
| Formato: | case study pictorial research tables/charts Journal Article |
| Publicado: |
HMP Global
Mar2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129789426&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 129789426 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10447946 YZM jtl: Wounds: A Compendium of Clinical Research & Practice issn: 10447946 maglogo: N pubinfo: dt: Mar2018 vid: 30 iid: 3 pid: 20465 pub: HMP Global place: Malvern, Pennsylvania artinfo: ui: 129789426 129789426 129789426 129789426 ppf: 57 ppct: 5 formats: tig: atl: Application of Viable Cryopreserved Human Placental Membrane Grafts in the Treatment of Wounds of Diverse Etiologies: A Case Series. aug: au: Anselmo, Derek S. McGuire, James B. Love, Ebony Vlahovic, Tracey affil: Resident Physician, Phoenixville Hospital, Phoenixville, PA sug: subj: Arteries Pathology Pyoderma Gangrenosum Surgery Pressure Ulcer Surgery Fetal Membranes Transplantation Placenta Transplantation Skin Transplantation Methods Cell Viability Cryopreservation Wound Care Wound Healing Recurrence Human Wounds, Chronic Therapy Photography Treatment Outcomes Retrospective Design Female Male Aged Aged, 80 and Over Aged: 65+ years Aged, 80 & over Female Male ab: There is evidence in the literature that viable cryopreserved human placental membrane (vCHPM) grafts are effective in treating diabetic foot ulcers and venous leg ulcers. Objective. This case series presents 3 cases of chronic ulcerations -- 1 arterial ulcer (AU), 1 pressure ulcer (PU), and 1 recurrence of a pyoderma gangrenosum ulcer (PGU) -- that had failed previous courses of standard wound care and were subsequently treated with vCHPM to determine if the treatment is an effective modality for treating wounds of these etiologies. Materials and Methods. This retrospective review describes 3 cases in which patients with chronic wounds that had failed standard of care treatments for more than 4 weeks were subsequently treated with weekly applications of vCHPM. Each wound area was recorded and photographed on a weekly basis and wound area reduction also was charted weekly. Results. The PU and AU both reached full closure in 4 and 5 weeks, respectively, without complication. The patient with the PGU achieved 64% closure after 9 applications of vCHPM. Conclusions. Viable CHPM is an effective treatment modality for wounds of diverse etiologies and shows better results than have been previously published with standard of care. In patients with PGUs, medical optimization and close management of comorbidities is essential in achieving optimal results. pubtype: Periodical doctype: case study pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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