Effect of the PiAstra Benchtop Flash-Heating Pasteurizer on Immune Factors of Donor Human Milk.

Introduction: PiAstra is a simulated flash-heat (FH) pasteurization temperature monitoring system designed using Raspberry Pi technology for the pasteurization of human milk. This study analyzed the effect of the PiAstra FH method on human milk immune components (immunoglobulin A [IgA] and lactoferr...

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Publicado en:Breastfeeding Medicine Vol. 13; no. 4; pp. 281 - 286
Autores principales: Daniels, Brodie, Reimers, Penny, King, Tracy, Schmidt, Stefan, Coutsoudis, Anna
Formato: research Journal Article
Publicado: Mary Ann Liebert, Inc. May2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2018
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      pub: Mary Ann Liebert, Inc.
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        10.1089/bfm.2018.0017
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        atl: Effect of the PiAstra Benchtop Flash-Heating Pasteurizer on Immune Factors of Donor Human Milk.
      aug:
        au:
          Daniels, Brodie
          Reimers, Penny
          King, Tracy
          Schmidt, Stefan
          Coutsoudis, Anna
        affil: Department of Paediatrics and Child Health, School of Clinical Medicine, University of KwaZulu-Natal, Durban, South Africa
      sug:
        subj:
          Milk, Human Immunology
          Milk Banks
          Heating Equipment and Supplies
          Pasteurization Equipment and Supplies
          Glycoproteins Immunology
          Female
          Immunoglobulins Analysis
          Pasteurization Methods
          Immunoglobulins Immunology
          Cost Benefit Analysis
          Heating Economics
          Human
          Glycoproteins Analysis
          Pasteurization Economics
          Transplant Donors
          Heat
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Questionnaires
          Female
      ab: Introduction: PiAstra is a simulated flash-heat (FH) pasteurization temperature monitoring system designed using Raspberry Pi technology for the pasteurization of human milk. This study analyzed the effect of the PiAstra FH method on human milk immune components (immunoglobulin A [IgA] and lactoferrin activity).Methods: Donor milk samples (N = 45) were obtained from a human milk bank, and pasteurized. Concentrations of IgA and lactoferrin activity were compared to their unpasteurized controls using the Student's t test.Results: The PiAstra FH method retained 34.2% of IgA (p < 0.0001) and 40.4% of lactoferrin activity (p < 0.0001) when compared to unpasteurized controls. The retention of IgA by the PiAstra is similar to previous FH studies, while retention of lactoferrin activity was higher than previous FH studies.Discussion: The high-technology, low-cost PiAstra system, which is able to retain vital immune components of human milk, provides safe donor milk for low-resourced settings. This enables the use of pasteurized donor milk when human milk is not available, potentially saving vulnerable infant lives.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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