Reexamining Metoclopramide's Role in the Prevention of Postoperative Nausea and Vomiting: A Secondary Analysis.
Postoperative nausea and vomiting (PONV) continue to be among the most undesirable and distressing complications following general anesthesia, affecting 20% to 30% of all surgical patients and up to 70% of patients with multiple known risk factors. The purpose of this study was to reexamine the effe...
| Publicado en: | AANA Journal Vol. 86; no. 3; pp. 212 - 219 |
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| Autor principal: | |
| Formato: | research tables/charts Journal Article |
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American Association of Nurse Anesthetists
Jun2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=129945910&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 129945910 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00946354 GLR jtl: AANA Journal issn: 00946354 maglogo: N pubinfo: dt: Jun2018 vid: 86 iid: 3 pid: 11824 pub: American Association of Nurse Anesthetists place: Park Ridge, Illinois artinfo: ui: 129945910 129945910 129945910 129945910 ppf: 212 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Reexamining Metoclopramide's Role in the Prevention of Postoperative Nausea and Vomiting: A Secondary Analysis. aug: au: Masiongale, Amy J. affil: Professor of biostatistics in the Department of Biostatistics and Epidemiology in the Medical College of Georgia at Augusta University sug: subj: Metoclopramide Administration and Dosage Postoperative Complications Nausea and Vomiting Human United States Ambulatory Surgery Anesthesia, General Data Analysis Software Descriptive Statistics Male Female Adult Middle Age Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Postoperative nausea and vomiting (PONV) continue to be among the most undesirable and distressing complications following general anesthesia, affecting 20% to 30% of all surgical patients and up to 70% of patients with multiple known risk factors. The purpose of this study was to reexamine the effectiveness of metoclopramide in the prevention of PONV when stratified by PONV risk scores. Secondary data from 2,116 adult ambulatory surgical patients were analyzed. Participants were, on average (SD), 49.7 (15.4) years of age, with a mean body mass index of 28.3 (6.9) kg/m², and were primarily female (65%). Risk scores for PONV ranged from 0 to 4, with a mean of 2.6 (1.0). Metoclopramide, 10 mg intravenously (IV) alone; metoclopramide, 10 mg IV, combined with ondansetron, 4 mg IV; and metoclopramide, 10 mg IV, combined with dexamethasone, 8 mg IV, and ondansetron, 4 mg IV, had a beneficial effect for adult ambulatory surgical patients with PONV risk scores of 1 to 4. Although this cohort study had limitations, future studies should investigate metoclopramide based on risk score recommendations, and guidelines should be reevaluated. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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