Accuracy and effectiveness of ultrasound-guided core-needle biopsy in the diagnosis of focal lesions in the salivary glands.

Objectives: To review the diagnostic accuracy of ultrasound-guided core-needle biopsy (CNB) in the diagnosis of salivary gland tumours (SGT).Methods: Retrospective, institutional review board approved, analysis of the CNB of SGT performed at our centre in 8 years. We used an automatic 18-G spring-lo...

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Publicado en:European Radiology Vol. 28; no. 7; pp. 2934 - 2942
Autores principales: del Cura, Jose Luis, Coronado, Gloria, Zabala, Rosa, Korta, Igone, López, Ignacio
Formato: Journal Article
Publicado: Springer Nature Jul2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00330-017-5295-9
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        atl: Accuracy and effectiveness of ultrasound-guided core-needle biopsy in the diagnosis of focal lesions in the salivary glands.
      aug:
        au:
          del Cura, Jose Luis
          Coronado, Gloria
          Zabala, Rosa
          Korta, Igone
          López, Ignacio
        affil: Radiology Department, Hospital Universitario Basurto, Bilbao, Spain
      sug:
        subj:
          Ultrasonography Methods
          Salivary Gland Neoplasms
          Salivary Gland Neoplasms Pathology
          Female
          Middle Age
          Sensitivity and Specificity
          Diagnosis, Differential
          Adolescence
          Biopsy Methods
          Young Adult
          Child, Preschool
          Male
          Aged, 80 and Over
          Adult
          Retrospective Design
          Salivary Glands
          Reproducibility of Results
          Child
          Salivary Glands Pathology
          Biopsy, Needle Methods
          Aged
          Scales
          Middle Aged: 45-64 years
          Adolescent: 13-18 years
          Child, Preschool: 2-5 years
          Aged, 80 & over
          Adult: 19-44 years
          Child: 6-12 years
          Aged: 65+ years
          Female
          Male
      ab: Objectives: To review the diagnostic accuracy of ultrasound-guided core-needle biopsy (CNB) in the diagnosis of salivary gland tumours (SGT).Methods: Retrospective, institutional review board approved, analysis of the CNB of SGT performed at our centre in 8 years. We used an automatic 18-G spring-loaded device. The final diagnosis was based on surgery in the cases that were operated on, and on clinical evolution and biopsy findings in the rest.Results: Four hundred and nine biopsies were performed in 381 patients (ages, 2-97 years; mean, 55.9). There were two minor complications. Biopsy was diagnostic in 98.3%. There were eight false negatives. The diagnostic values for malignancy were: sensitivity 89.6%, specificity 100%, positive predictive value (PPV) 100% and negative predictive value (NPV) 98%. For the detection of neoplasms were: sensitivity 98.7%, specificity 99%, PPV 99.7% and VPN 96.1%.Conclusions: Accuracy of CNB in SGT is very high, with a very high sensitivity and an absolutely reliable diagnosis of malignancy. Complication rate is very low. It should be considered the technique of choice when a STG is detected. Normal tissue results warrant repeating biopsy.Key Points: • Ultrasound-guided core-biopsy is the technique of choice in salivary glands nodules • Sensitivity, specificity for detecting neoplasms (which should be resected) are around 99% • Diagnosis of malignancy in core-biopsy is absolutely reliable • A CNB result of "normal tissue", however, warrants repeating the biopsy • Complication rate is very low.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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