Profiling Arthritis Pain with a Decision Tree.

Abstract: Background: Arthritis is the leading cause of work disability and contributes to lost productivity. Previous studies showed that various factors predict pain, but they were limited in sample size and scope from a data analytics perspective. Objectives: The current study applied machine lea...

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Published in:Pain Practice Vol. 18; no. 5; pp. 568 - 580
Main Authors: Hung, Man, Bounsanga, Jerry, Liu, Fangzhou, Voss, Maren W.
Format: research tables/charts Journal Article
Published: Wiley-Blackwell Jun2018
Online Access:View this record in EBSCOhost
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      dt: Jun2018
      vid: 18
      iid: 5
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/papr.12645
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        atl: Profiling Arthritis Pain with a Decision Tree.
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          Hung, Man
          Bounsanga, Jerry
          Liu, Fangzhou
          Voss, Maren W.
        affil: Department of Orthopaedics, University of Utah, Salt Lake City, Utah, U.S.A.
      sug:
        subj:
          Arthritis Complications
          Pain Etiology
          Decision Trees
          Machine Learning
          Algorithms
          Human
          Surveys
          Data Mining
          Billing and Claims
          Patient-Reported Outcomes
          Social Behavior
          Medical Records
          Data Analysis, Statistical
          Sensitivity and Specificity
          Functional Assessment
          Cost Benefit Analysis
          Pain Risk Factors
          Stair Climbing
      ab: Abstract: Background: Arthritis is the leading cause of work disability and contributes to lost productivity. Previous studies showed that various factors predict pain, but they were limited in sample size and scope from a data analytics perspective. Objectives: The current study applied machine learning algorithms to identify predictors of pain associated with arthritis in a large national sample. Methods: Using data from the 2011 to 2012 Medical Expenditure Panel Survey, data mining was performed to develop algorithms to identify factors and patterns that contribute to risk of pain. The model incorporated over 200 variables within the algorithm development, including demographic data, medical claims, laboratory tests, patient‐reported outcomes, and sociobehavioral characteristics. Results: The developed algorithms to predict pain utilize variables readily available in patient medical records. Using the machine learning classification algorithm J48 with 50‐fold cross‐validations, we found that the model can significantly distinguish those with and without pain (c‐statistics = 0.9108). The F measure was 0.856, accuracy rate was 85.68%, sensitivity was 0.862, specificity was 0.852, and precision was 0.849. Conclusion: Physical and mental function scores, the ability to climb stairs, and overall assessment of feeling were the most discriminative predictors from the 12 identified variables, predicting pain with 86% accuracy for individuals with arthritis. In this era of rapid expansion of big data application, the nature of healthcare research is moving from hypothesis‐driven to data‐driven solutions. The algorithms generated in this study offer new insights on individualized pain prediction, allowing the development of cost‐effective care management programs for those experiencing arthritis pain.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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