Association of Efficacy of Resistance Exercise Training With Depressive Symptoms: Meta-analysis and Meta-regression Analysis of Randomized Clinical Trials.
Importance: The physical benefits of resistance exercise training (RET) are well documented, but less is known regarding the association of RET with mental health outcomes. To date, no quantitative synthesis of the antidepressant effects of RET has been conducted.Objectives: To estimate the associat...
| Publicado en: | JAMA Psychiatry Vol. 75; no. 6; pp. 566 - 577 |
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| Autores principales: | , , , , , |
| Formato: | research Journal Article |
| Publicado: |
American Medical Association
Jun2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130012484&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 130012484 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2168622X FT4X jtl: JAMA Psychiatry issn: 2168622X maglogo: N pubinfo: dt: Jun2018 vid: 75 iid: 6 pid: 30 pub: American Medical Association place: Chicago, Illinois artinfo: ui: 130012484 130012484 NLM29800984 130012484 10.1001/jamapsychiatry.2018.0572 NLM29800984 130012484 ppf: 566 ppct: 11 formats: tig: atl: Association of Efficacy of Resistance Exercise Training With Depressive Symptoms: Meta-analysis and Meta-regression Analysis of Randomized Clinical Trials. aug: au: Gordon, Brett R. McDowell, Cillian P. Hallgren, Mats Meyer, Jacob D. Lyons, Mark Herring, Matthew P. affil: Department of Physical Education and Sport Sciences, University of Limerick, Limerick, Ireland sug: subj: Resistance Training Methods Depression Therapy Clinical Trials Human Regression Depression Psychosocial Factors Meta Analysis Validation Studies Comparative Studies Evaluation Research Multicenter Studies Exercise of Self-Care Agency Scale Ferrans and Powers Quality of Life Index Scales ab: Importance: The physical benefits of resistance exercise training (RET) are well documented, but less is known regarding the association of RET with mental health outcomes. To date, no quantitative synthesis of the antidepressant effects of RET has been conducted.Objectives: To estimate the association of efficacy of RET with depressive symptoms and determine the extent to which logical, theoretical, and/or prior empirical variables are associated with depressive symptoms and whether the association of efficacy of RET with depressive symptoms accounts for variability in the overall effect size.Data Sources: Articles published before August 2017, located using Google Scholar, MEDLINE, PsycINFO, PubMed, and Web of Science.Study Selection: Randomized clinical trials included randomization to RET (n = 947) or a nonactive control condition (n = 930).Data Extraction and Synthesis: Hedges d effect sizes were computed and random-effects models were used for all analyses. Meta-regression was conducted to quantify the potential moderating influence of participant and trial characteristics.Main Outcomes and Measures: Randomized clinical trials used validated measures of depressive symptoms assessed at baseline and midintervention and/or postintervention. Four primary moderators were selected a priori to provide focused research hypotheses about variation in effect size: total volume of prescribed RET, whether participants were healthy or physically or mentally ill, whether or not allocation and/or assessment were blinded, and whether or not the RET intervention resulted in a significant improvement in strength.Results: Fifty-four effects were derived from 33 randomized clinical trials involving 1877 participants. Resistance exercise training was associated with a significant reduction in depressive symptoms with a moderate-sized mean effect ∆ of 0.66 (95% CI, 0.48-0.83; z = 7.35; P < .001). Significant heterogeneity was indicated (total Q = 216.92, df = 53; P < .001; I2 = 76.0% [95% CI, 72.7%-79.0%]), and sampling error accounted for 32.9% of observed variance. The number needed to treat was 4. Total volume of prescribed RET, participant health status, and strength improvements were not significantly associated with the antidepressant effect of RET. However, smaller reductions in depressive symptoms were derived from randomized clinical trials with blinded allocation and/or assessment.Conclusions and Relevance: Resistance exercise training significantly reduced depressive symptoms among adults regardless of health status, total prescribed volume of RET, or significant improvements in strength. Better-quality randomized clinical trials blinding both allocation and assessment and comparing RET with other empirically supported treatments for depressive symptoms are needed. pubtype: Academic Journal doctype: meta analysis research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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