Neuropeptide B and Vaspin as New Biomarkers in Anorexia Nervosa.
Introduction. The aim of the study was to assess the correlation between the levels of neuropeptide B (NPB), neuropeptide W (NPW), vaspin (VAS), and the total antioxidant status (TAS) in the blood, as well as nutritional status of patients with anorexia nervosa (AN). Materials and Methods. The study...
| Published in: | BioMed Research International Vol. 2018; pp. 1 - 9 |
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| Main Authors: | , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
6/10/2018
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130075386&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 130075386 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23146133 FT2T jtl: BioMed Research International issn: 23146133 maglogo: N pubinfo: dt: 6/10/2018 vid: 2018 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 130075386 130075386 130075386 10.1155/2018/9727509 130075386 ppf: 1 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Neuropeptide B and Vaspin as New Biomarkers in Anorexia Nervosa. aug: au: Grzelak, Teresa Tyszkiewicz-Nwafor, Marta Dutkiewicz, Agata Mikulska, Aniceta Ada Dmitrzak-Weglarz, Monika Slopien, Agnieszka Czyzewska, Krystyna Paszynska, Elzbieta affil: Division of Biology of Civilization-Linked Diseases, Department of Chemistry and Clinical Biochemistry, Poznan University of Medical Sciences, Swiecickiego 6, 60-781 Poznan, Poland sug: subj: Anorexia Nervosa Diagnosis Neuropeptides Blood Adipokines Blood Antioxidants Nutritional Status Biological Markers Human Female Child Adolescence Body Weight Anthropometry Correlation Coefficient Child: 6-12 years Adolescent: 13-18 years Female ab: Introduction. The aim of the study was to assess the correlation between the levels of neuropeptide B (NPB), neuropeptide W (NPW), vaspin (VAS), and the total antioxidant status (TAS) in the blood, as well as nutritional status of patients with anorexia nervosa (AN). Materials and Methods. The study covered a cohort of 76 female teenagers, including 46 females with extreme AN and 30 healthy peers (CONTR) aged 12-17. Results. AN persons were characterized by higher (in comparison to CONTR) NPB and VAS concentrations and lower values of TAS levels, body weight, and anthropometric values. Positive correlations between NPB and VAS levels were noted in the AN group (R=0.33; p<0.001) as well as between concentrations of NPW and VAS in the same group (R=0.49; p<0.001). Furthermore, positive correlations existed between NPB and NPW concentrations across the whole studied population (AN+CONTR; R=0.75; p<0.000001), AN (R=0.73; p<0.000001) and CONTR (R=0.90; p<0.0005). Conclusions. In detailed diagnostics of AN it is worth considering testing NPB and VAS levels. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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