Management of Facial Pyoderma Gangrenosum Using Platelet-Rich Fibrin: A Technical Report.

This report describes a case of local pyoderma gangrenosum that was treated with short-term immunosuppressive therapy and the topical application of platelet-rich fibrin (PRF). Medical treatment included oral corticosteroid therapy and topical treatment with PRF in solid and liquid form. This therap...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Oral & Maxillofacial Surgery (02782391) Vol. 76; no. 7; pp. 1460 - 1464
Autores principales: Fortunato, Leonzio, Barone, Selene, Bennardo, Francesco, Giudice, Amerigo
Formato: case study Journal Article
Publicado: W B Saunders Jul2018
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130123156&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 130123156
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        02782391
        1YP
      jtl: Journal of Oral & Maxillofacial Surgery (02782391)
      issn: 02782391
      maglogo: N
    pubinfo:
      dt: Jul2018
      vid: 76
      iid: 7
      pid: 1351
      pub: W B Saunders
      place: Philadelphia, Pennsylvania
    artinfo:
      ui:
        130123156
        130123156
        NLM29425752
        130123156
        10.1016/j.joms.2018.01.012
        NLM29425752
        130123156
      ppf: 1460
      ppct: 4
      formats:
      tig:
        atl: Management of Facial Pyoderma Gangrenosum Using Platelet-Rich Fibrin: A Technical Report.
      aug:
        au:
          Fortunato, Leonzio
          Barone, Selene
          Bennardo, Francesco
          Giudice, Amerigo
        affil: Associate Professor, School of Dentistry, Department of Health Sciences, Magna Graecia University of Catanzaro, Catanzaro, Italy
      sug:
        subj:
          Pyoderma Gangrenosum Drug Therapy
          Face
          Female
          Middle Age
          Administration, Topical
          Adrenal Cortex Hormones Administration and Dosage
          Short Portable Mental Status Questionnaire
          Middle Aged: 45-64 years
          Female
      ab: This report describes a case of local pyoderma gangrenosum that was treated with short-term immunosuppressive therapy and the topical application of platelet-rich fibrin (PRF). Medical treatment included oral corticosteroid therapy and topical treatment with PRF in solid and liquid form. This therapy initially led to the reduction of the ulcer's size and an improvement in symptoms, until the ulcer was completely healed after a few weeks. A relapse was treated with only the application of PRF to the affected tissue with excellent recovery. The efficacy of PRF as a guide for wound healing is a result of the continuous release of growth factors involved in tissue repair mechanisms. PRF has proved to be suitable for the management of facial pyoderma gangrenosum while allowing a reduction in systemic corticosteroid therapy. The ease of preparation, low cost, and outpatient use make PRF an optimal scaffold for tissue healing processes.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N