An Assessment of the Clinical Accuracy of Ultrasound in Diagnosing Cirrhosis in the Absence of Portal Hypertension.

Ultrasound is an invaluable tool for the diagnosis of hepatocellular carcinoma and portal hypertension. However, the accuracy of ultrasound in diagnosing cirrhosis in the absence of portal hypertension has not been well studied. Using the specific terms cirrhosis or nodular(ity), a retrospective eva...

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Publicado en:Gastroenterology & Hepatology Vol. 14; no. 6; pp. 367 - 374
Autores principales: Kelly, Erin M. M., Feldstein, Vickie A., Parks, Monica, Hudock, Rebecca, Etheridge, Dustin, Peters, Marion G.
Formato: research tables/charts Journal Article
Publicado: Gastro-Hep Communications, Inc Jun2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2018
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        atl: An Assessment of the Clinical Accuracy of Ultrasound in Diagnosing Cirrhosis in the Absence of Portal Hypertension.
      aug:
        au:
          Kelly, Erin M. M.
          Feldstein, Vickie A.
          Parks, Monica
          Hudock, Rebecca
          Etheridge, Dustin
          Peters, Marion G.
        affil: Assistant professor of medicine in the Division of Gastroenterology and Hepatology at the University of Ottawa in Ottawa, Canada
      sug:
        subj:
          Liver Cirrhosis Ultrasonography
          Hypertension, Portal
          Sensitivity and Specificity
          Human
          Carcinoma, Hepatocellular Ultrasonography
          Retrospective Design
          Abdomen Ultrasonography
          Record Review
          Biopsy
          Patient-Reported Outcomes
          Ultrasonography Methods
          Severity of Illness
      ab: Ultrasound is an invaluable tool for the diagnosis of hepatocellular carcinoma and portal hypertension. However, the accuracy of ultrasound in diagnosing cirrhosis in the absence of portal hypertension has not been well studied. Using the specific terms cirrhosis or nodular(ity), a retrospective evaluation was conducted on abdominal ultrasounds performed between 2008 and 2013. Patients with evidence of portal hypertension were excluded from the evaluation. Charts were reviewed for evidence of cirrhosis on liver biopsy performed within 1 year of the ultrasound. Of the 69 patients whose ultrasound findings reported cirrhosis without portal hypertension who underwent liver biopsy, 47 (68%) had histologic evidence of cirrhosis. When patients with advanced fibrosis (F3 or F4) on liver biopsy were included, the sensitivity of the ultrasound improved to 80%. One in 5 biopsies showed only mild to moderate or no fibrosis (F0-F2). Sonographic assessment by experts may falsely suggest or overestimate cirrhosis. In the absence of objective evidence of portal hypertension, caution should be taken in diagnosing cirrhosis based on sonographic interpretation alone.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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