Magnetic resonance assessment of fetal lung maturity: comparison between signal intensity and volume measurement.

Purpose: We evaluated the associations between gestational age (GA) and lung-to-liver signal intensity ratio (LLSIR) and fetal lung volume (FLV) using magnetic resonance imaging (MRI). Moreover, we evaluated the reproducibility of these measurements.Materials and Methods: LLSIR and FLV were measured...

Full description

Bibliographic Details
Published in:Japanese Journal of Radiology Vol. 36; no. 7; pp. 444 - 450
Main Authors: Ogawa, Ryo, Kido, Tomoyuki, Nakamura, Masashi, Kido, Teruhito, Mochizuki, Teruhito, Sugiyama, Takashi
Format: research Journal Article
Published: Springer Nature Jul2018
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130275517&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 130275517
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        18671071
        AUCM
      jtl: Japanese Journal of Radiology
      issn: 18671071
      maglogo: N
    pubinfo:
      dt: Jul2018
      vid: 36
      iid: 7
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        130275517
        130275517
        NLM29767297
        130275517
        10.1007/s11604-018-0745-0
        NLM29767297
        130275517
      ppf: 444
      ppct: 6
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Magnetic resonance assessment of fetal lung maturity: comparison between signal intensity and volume measurement.
      aug:
        au:
          Ogawa, Ryo
          Kido, Tomoyuki
          Nakamura, Masashi
          Kido, Teruhito
          Mochizuki, Teruhito
          Sugiyama, Takashi
        affil: Department of Radiology, Ehime University Graduate School of Medicine, Shitsukawa, 791-0295, Toon, Ehime, Japan
      sug:
        subj:
          Magnetic Resonance Imaging Methods
          Lung Anatomy and Histology
          Lung Embryology
          Female
          Reproducibility of Results
          Liver
          Body Weights and Measures
          Gestational Age
          Liver Embryology
          Retrospective Design
          Liver Anatomy and Histology
          Human
          Lung
          Pregnancy
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Clinical Assessment Tools
          Female
      ab: Purpose: We evaluated the associations between gestational age (GA) and lung-to-liver signal intensity ratio (LLSIR) and fetal lung volume (FLV) using magnetic resonance imaging (MRI). Moreover, we evaluated the reproducibility of these measurements.Materials and Methods: LLSIR and FLV were measured using single-shot fast spin-echo MRI in 88 consecutive fetuses. The Spearman test was used to assess the relationships between (1) LLSIR and GA, and (2) FLV and GA in 81 fetuses without lung abnormalities. Intra- and inter-observer reliabilities were assessed using intra-class correlation coefficients (ICCs).Results: Overall, GA and LLSIR were significantly correlated (r = 0.62, p < 0.001). However, GA and LLSIR were only significantly correlated during the third trimester (before third trimester: r = 0.39, p = 0.08; during third trimester: r = 0.46, p < 0.001). Overall, GA and FLV were significantly correlated (r = 0.72, p < 0.001). FLV was significantly correlated with GA before (r = 0.86, p < 0.001) and during the third trimester (r = 0.47, p < 0.001). All ICCs were above 0.90.Conclusions: LLSIR and FLV are useful for the assessment of fetal lung maturity and are highly reproducible. Before the third trimester, FLV is more suitable than LLSIR for the evaluation of fetal lung maturity.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N