SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer.
Background: Endocrine resistance in estrogen receptor-positive (ER+) breast cancer is a major clinical problem and is associated with accelerated cancer cell growth, increased motility and acquisition of mesenchymal characteristics. However, the specific molecules and pathways involved in these alte...
| Published in: | Breast Cancer Research Vol. 20; no. 1 |
|---|---|
| Main Authors: | , , , , |
| Format: | research Journal Article |
| Published: |
BioMed Central
6/19/2018
|
| Online Access: | View this record in EBSCOhost |