Ultrasensitive Detection of Chimerism by Single-Molecule Molecular Inversion Probe Capture and High-Throughput Sequencing of Copy Number Deletion Polymorphisms.

BACKGROUND: Genomic chimerism, the co-occurrence of cells from different genetic origins, provides important diagnostic information in diverse clinical contexts, including graft injury detection and longitudinal surveillance of hematopoietic stem cell transplantation patients, but existing assays ar...

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Bibliographic Details
Published in:Clinical Chemistry Vol. 64; no. 6; pp. 938 - 950
Main Authors: Wu, David, Waalkes, Adam, Penewit, Kelsi, Salipante, Stephen J.
Format: Journal Article
Published: Oxford University Press / USA Jun2018
Online Access:View this record in EBSCOhost