Diagnostic Accuracy of the Veteran Affairs' Traumatic Brain Injury Screen.

Objective To comprehensively estimate the diagnostic accuracy and reliability of the Department of Veterans Affairs (VA) Traumatic Brain Injury (TBI) Clinical Reminder Screen (TCRS). Design Cross-sectional, prospective, observational study using the Standards for Reporting of Diagnostic Accuracy cri...

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Publicado en:Archives of Physical Medicine & Rehabilitation Vol. 99; no. 7; pp. 1370 - 1383
Autores principales: Pape, Theresa Louise Bender, Smith, Bridget, Babcock-Parziale, Judith, Evans, Charlesnika T., Herrold, Amy A., Phipps Maieritsch, Kelly, Jr.High, Walter M.
Formato: research Journal Article
Publicado: W B Saunders Jul2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2018
      vid: 99
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      pub: W B Saunders
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        10.1016/j.apmr.2017.11.017
        130301583
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        atl: Diagnostic Accuracy of the Veteran Affairs' Traumatic Brain Injury Screen.
      aug:
        au:
          Pape, Theresa Louise Bender
          Smith, Bridget
          Babcock-Parziale, Judith
          Evans, Charlesnika T.
          Herrold, Amy A.
          Phipps Maieritsch, Kelly
          Jr.High, Walter M.
        affil: Department of Veterans Affairs (VA), Research Service, Edward Hines Jr. VA Hospital, Hines, IL
      sug:
        subj:
          Brain Injuries Diagnosis
          Neuropsychological Tests
          Instrument Validation
          Human
          Cross Sectional Studies
          Prospective Studies
          Nonexperimental Studies
          Hospitals, Veterans
          Multicenter Studies
          Validation Studies
          Veterans
          Structured Interview
          Sensitivity and Specificity
          Predictive Value of Tests
          Descriptive Statistics
          Odds Ratio
          Stress Disorders, Post-Traumatic Diagnosis
      ab: Objective To comprehensively estimate the diagnostic accuracy and reliability of the Department of Veterans Affairs (VA) Traumatic Brain Injury (TBI) Clinical Reminder Screen (TCRS). Design Cross-sectional, prospective, observational study using the Standards for Reporting of Diagnostic Accuracy criteria. Setting Three VA Polytrauma Network Sites. Participants Operation Iraqi Freedom, Operation Enduring Freedom veterans (N=433). Main Outcome Measures TCRS, Comprehensive TBI Evaluation, Structured TBI Diagnostic Interview, Symptom Attribution and Classification Algorithm, and Clinician-Administered Posttraumatic Stress Disorder (PTSD) Scale. Results Forty-five percent of veterans screened positive on the TCRS for TBI. For detecting occurrence of historical TBI, the TCRS had a sensitivity of .56 to .74, a specificity of .63 to .93, a positive predictive value (PPV) of 25% to 45%, a negative predictive value (NPV) of 91% to 94%, and a diagnostic odds ratio (DOR) of 4 to 13. For accuracy of attributing active symptoms to the TBI, the TCRS had a sensitivity of .64 to .87, a specificity of .59 to .89, a PPV of 26% to 32%, an NPV of 92% to 95%, and a DOR of 6 to 9. The sensitivity was higher for veterans with PTSD (.80–.86) relative to veterans without PTSD (.57–.82). The specificity, however, was higher among veterans without PTSD (.75–.81) relative to veterans with PTSD (.36–.49). All indices of diagnostic accuracy changed when participants with questionably valid (QV) test profiles were eliminated from analyses. Conclusions The utility of the TCRS to screen for mild TBI (mTBI) depends on the stringency of the diagnostic reference standard to which it is being compared, the presence/absence of PTSD, and QV test profiles. Further development, validation, and use of reproducible diagnostic algorithms for symptom attribution after possible mTBI would improve diagnostic accuracy.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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