Chromosomal mosaicism in human blastocysts: the ultimate challenge of preimplantation genetic testing?

Study Question: To what extent does a trophectoderm (TE) biopsy reliably reflect the chromosomal constitution of the inner cell mass (ICM) in human blastocysts?Summary Answer: Concordance between TE and ICM was established in 62.1% of the embryos analysed.What Is Known Already: Next generation seque...

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Publicado en:Human Reproduction Vol. 33; no. 7; pp. 1 - 19
Autores principales: Popovic, M., Dheedene, A., Christodoulou, C., Taelman, J., Dhaenens, L., Van Nieuwerburgh, F., Deforce, D., Van den Abbeel, E., De Sutter, P., Menten, B., Heindryckx, B.
Formato: research Journal Article
Publicado: Oxford University Press / USA Jul2018
Acceso en línea:Ver este registro en EBSCOhost