Separating arterial pressure increases and decreases in assessing cardiac baroreflex sensitivity via sequence and bivariate phase-rectified signal averaging techniques.

Cardiac baroreflex (cBR) is activated by both arterial pressure (AP) increases and decreases. Sequence method, a widely utilized tool assessing cBR sensitivity (cBRS) from spontaneous heart period (HP) and systolic AP (SAP) variations, allows the separated computation of cBRS from positive and negat...

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Publicado en:Medical & Biological Engineering & Computing Vol. 56; no. 7; pp. 1241 - 1253
Autores principales: De Maria, Beatrice, Bari, Vlasta, Ranucci, Marco, Pistuddi, Valeria, Ranuzzi, Giovanni, Takahashi, Anielle C. M., Catai, Aparecida M., Dalla Vecchia, Laura, Cerutti, Sergio, Porta, Alberto
Formato: Journal Article
Publicado: Springer Nature Jul2018
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Separating arterial pressure increases and decreases in assessing cardiac baroreflex sensitivity via sequence and bivariate phase-rectified signal averaging techniques.
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          De Maria, Beatrice
          Bari, Vlasta
          Ranucci, Marco
          Pistuddi, Valeria
          Ranuzzi, Giovanni
          Takahashi, Anielle C. M.
          Catai, Aparecida M.
          Dalla Vecchia, Laura
          Cerutti, Sergio
          Porta, Alberto
        affil: IRCCS Istituti Clinici Scientifici Maugeri, Istituto di Milano, Milan, Italy
      sug:
        subj:
          Signal Processing, Computer Assisted
          Heart Physiology
          Baroreflex Physiology
          Arterial Pressure Physiology
          Systole Physiology
          Aged
          Coronary Artery Bypass
          Young Adult
          Middle Age
          Aged, 80 and Over
          Female
          Male
          Adult
          Behavior Rating Scales
          Questionnaires
          Aged: 65+ years
          Middle Aged: 45-64 years
          Aged, 80 & over
          Adult: 19-44 years
          Female
          Male
      ab: Cardiac baroreflex (cBR) is activated by both arterial pressure (AP) increases and decreases. Sequence method, a widely utilized tool assessing cBR sensitivity (cBRS) from spontaneous heart period (HP) and systolic AP (SAP) variations, allows the separated computation of cBRS from positive and negative SAP variations. The recently proposed phase-rectified signal averaging (PRSA) method has the same feature but it has been applied so far solely to positive SAP variations. We adapted the PRSA method to compute cBRS over negative SAP variations and we compared the results with those derived from sequence method over two protocols: (i) graded head-up tilt (HUT) at 15, 30, 45, 60, and 75° in 19 healthy subjects and (ii) general anesthesia induction in 118 patients undergoing coronary artery bypass graft surgery. Regardless of the sign of SAP changes and method, cBRS moved toward 0 during HUT. Only sequence method detected the cBRS decrease after general anesthesia induction. In both protocols, the correlation between the PRSA-based cBRSs derived from positive and negative SAP changes was higher than that obtained from analogous sequence-based cBRSs and correlation between equivalent cBRSs derived from different methods might be absent. We conclude that the two methods are not interchangeable in assessing cBRS. Graphical abstract Graphical representation of the baroreflex sensitivity (BRS) estimation procedures carried out using sequence (SEQ) and phase-rectified signal averaging (PRSA) techniques over spontaneous fluctuations of heart period (HP) and systolic arterial pressure (SAP). BRSSEQ and BRSPRSA was separately computed over positive (+) and negative (-) SAP variations.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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