Plantar blood flow response to accumulated pressure stimulus in diabetic people with different peak plantar pressure: a non-randomized clinical trial.

The aim of this study was to investigate the plantar blood flow response to the same accumulated pressure stimulus in diabetic patients with different peak plantar pressure (PPP), which is important for assessing the risk of diabetic foot ulcer. Eleven diabetic subjects with high PPP (PPP ≥ 207 kPa)...

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Publicado en:Medical & Biological Engineering & Computing Vol. 56; no. 7; pp. 1127 - 1135
Autores principales: Pu, Fang, Ren, Weiyan, Fu, Hongyuan, Zheng, Xuan, Yang, Min, Jan, Yih-Kuen, Fan, Yubo
Formato: clinical trial research Journal Article
Publicado: Springer Nature Jul2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2018
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11517-018-1836-x
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        atl: Plantar blood flow response to accumulated pressure stimulus in diabetic people with different peak plantar pressure: a non-randomized clinical trial.
      aug:
        au:
          Pu, Fang
          Ren, Weiyan
          Fu, Hongyuan
          Zheng, Xuan
          Yang, Min
          Jan, Yih-Kuen
          Fan, Yubo
        affil: Key Laboratory of Rehabilitation Technical Aids of Ministry of Civil Affair, School of Biological Science and Medical Engineering, Beihang University, No.37 Xueyuan Road, Haidian District, 100191, Beijing, People’s Republic of China
      sug:
        subj:
          Pressure
          Foot Physiopathology
          Foot Blood Supply
          Diabetic Foot Physiopathology
          Male
          Human
          Time Factors
          Demography
          Female
          Aged
          Perfusion
          Blood Circulation
          Clinical Trials
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Funding Source
          Aged: 65+ years
          Male
          Female
      ab: The aim of this study was to investigate the plantar blood flow response to the same accumulated pressure stimulus in diabetic patients with different peak plantar pressure (PPP), which is important for assessing the risk of diabetic foot ulcer. Eleven diabetic subjects with high PPP (PPP ≥ 207 kPa) and 8 diabetic subjects with low PPP (PPP < 207 kPa) were asked to walk naturally on a treadmill so as to induce an accumulated stimulus of 73,000 kPa·s on their first metatarsal head, which was monitored with a sensorized insole. Blood perfusion (BP) in the first metatarsal head was measured before and after walking. Results showed that blood flow after applying the same walking stimulus was significantly decreased in comparison to the basal BP before walking in both high PPP and low PPP groups (p < 0.05), but no significant differences were found between the two groups in terms of BP parameters and its percentage change (p > 0.05). Moreover, BP parameters were not significantly correlated to PPP and the pressure-time integral (PTI) of the subjects' gait (p > 0.05). This indicated that, besides PPP and PTI, the accumulated mechanical stimulus should be taken into consideration when assessing the risk of diabetic patients developing foot ulcers. Graphical abstract Plantar blood flow response to a walking stimulus.
      pubtype: Academic Journal
      doctype:
        clinical trial
        research
        Journal Article
      ougenre: Article
    language: English
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