Cyclic Thiosulfinates and Cyclic Disulfides Selectively Cross-Link Thiols While Avoiding Modification of Lone Thiols.

This work addresses the need for chemical tools that can selectively form cross-links. Contemporary thiol-selective cross-linkers, for example, modify all accessible thiols, but only form cross-links between a subset. The resulting terminal "dead-end" modifications of lone thiols are toxic, confound...

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Publicado en:	Journal of the American Chemical Society Vol. 140; no. 24; pp. 7377 - 7381
Autores principales:	Donnelly, Daniel P., Dowgiallo, Matthew G., Salisbury, Joseph P., Aluri, Krishna C., Iyengar, Suhasini, Chaudhari, Meenal, Mathew, Merlit, Miele, Isabella, Auclair, Jared R., Lopez, Steven A., Manetsch, Roman, Agar, Jeffrey N.
Formato:	Artículo
Publicado:	American Chemical Society 6/20/2018
Materias:	Disulfides Thiols Superoxide dismutase Lipoic acid Density functional theory
Acceso en línea:	Ver este registro en EBSCOhost