Characterization of the endolysosomal system in human chordoma cell lines: is there a role of lysosomes in chemoresistance of this rare bone tumor?

Chordoma is a rare tumor of the bone derived from remnants of the notochord with pronounced chemoresistance. A common feature of the notochord and chordoma cells is distinct vacuolization. Recently, the notochord vacuole was described as a lysosome-related organelle. Since lysosomes are considered a...

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Publicado en:Histochemistry & Cell Biology Vol. 150; no. 1; pp. 83 - 93
Autores principales: Kolb-Lenz, Dagmar, Fuchs, Robert, Lohberger, Birgit, Heitzer, Ellen, Meditz, Katharina, Pernitsch, Dominique, Pritz, Elisabeth, Groselj-Strele, Andrea, Leithner, Andreas, Liegl-Atzwanger, Bernadette, Rinner, Beate
Formato: Journal Article
Publicado: Springer Nature Jul2018
Acceso en línea:Ver este registro en EBSCOhost