Psychologic and psychoeducational consequences of thyroxine therapy for juvenile acquired hypothyroidism.
The observation of severe behavioral reactions or learning problems in three teenagers treated with L-thyroxine for juvenile acquired hypothyroidism prompted us to conduct a prospective study of achievement and behavioral characteristics of patients with newly diagnosed juvenile acquired hypothyroid...
| Publicado en: | Journal of Pediatrics Vol. 122; no. 4; pp. 543 - 550 |
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| Autores principales: | , , |
| Formato: | case study research Journal Article |
| Publicado: |
Elsevier B.V.
1993 Apr
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130496502&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 130496502 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00223476 04M jtl: Journal of Pediatrics issn: 00223476 maglogo: N pubinfo: dt: 1993 Apr vid: 122 iid: 4 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 130496502 130496502 NLM8463898 130496502 10.1016/s0022-3476(05)83533-4 NLM8463898 130496502 ppf: 543 ppct: 7 formats: tig: atl: Psychologic and psychoeducational consequences of thyroxine therapy for juvenile acquired hypothyroidism. aug: au: Rovet, J F Daneman, D Bailey, J D affil: Department of Psychology, Hospital for Sick Children, Toronto, Canada sug: subj: Learning Disorders Chemically Induced Thyroxine Adverse Effects Hypothyroidism Drug Therapy Hypothyroidism Psychosocial Factors Child Behavior Disorders Chemically Induced Intelligence Tests Psychological Tests Learning Disorders Epidemiology Prospective Studies Thyroxine Therapeutic Use Child Behavior Disorders Epidemiology Hypothyroidism Epidemiology Incidence Human Adolescence Child Female Male Validation Studies Comparative Studies Evaluation Research Multicenter Studies Clinical Assessment Tools Adolescent: 13-18 years Child: 6-12 years Female Male ab: The observation of severe behavioral reactions or learning problems in three teenagers treated with L-thyroxine for juvenile acquired hypothyroidism prompted us to conduct a prospective study of achievement and behavioral characteristics of patients with newly diagnosed juvenile acquired hypothyroidism. On diagnosis of juvenile acquired hypothyroidism and before treatment with L-thyroxine, 23 children and adolescents underwent a comprehensive battery of psychoeducational tests, which was repeated after 3, 12, and 24 months of replacement therapy. Results revealed that adverse behavioral reactions and learning problems were relatively rare in these children, although symptoms of juvenile acquired hypothyroidism were associated with increased distractibility, hyperactivity, and poorer achievement. The least gain in achievement was made by children with more severe hypothyroidism at diagnosis; children with the best psychologic outcome were those who achieved euthyroidism more slowly. We conclude that severe behavioral manifestations of L-thyroxine therapy for juvenile acquired hypothyroidism are uncommon, but mild behavioral symptoms and poorer school achievement may occur in about 25% of patients, who represent the most severe cases at diagnosis. pubtype: Academic Journal doctype: case study research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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