Dosimetric variations in calculation grid size in prostate VMAT: a dose-volume histogram analysis using the Gaussian error function.
Background: Varying the calculation grid size can change the results of dose-volume and radiobiological parameters in a treatment plan, and therefore has an impact on the treatment planning quality assurance. Purpose: This study investigated the dosimetric influence of the calculation grid size vari...
| Publicado en: | Journal of Radiotherapy in Practice Vol. 17; no. 2; pp. 162 - 171 |
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| Autores principales: | , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
Cambridge University Press
Jun2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130500907&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 130500907 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 14603969 8OJ jtl: Journal of Radiotherapy in Practice issn: 14603969 maglogo: N pubinfo: dt: Jun2018 vid: 17 iid: 2 pid: 15979 pub: Cambridge University Press artinfo: ui: 130500907 130500907 130500907 10.1017/S1460396917000619 130500907 ppf: 162 ppct: 9 formats: tig: atl: Dosimetric variations in calculation grid size in prostate VMAT: a dose-volume histogram analysis using the Gaussian error function. aug: au: Chow, James C. L. Jiang, Runqing Markel, Daniel affil: Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Canada sug: subj: Dosimetry Prostatic Neoplasms Radiotherapy Radiotherapy, Conformal Methods Human Radiobiology Rectum Radiation Effects Bladder Radiation Effects Femur Radiation Effects Radiologists Radiation Dosage Quality Assurance ab: Background: Varying the calculation grid size can change the results of dose-volume and radiobiological parameters in a treatment plan, and therefore has an impact on the treatment planning quality assurance. Purpose: This study investigated the dosimetric influence of the calculation grid size variation in the prostate volumetric modulated arc therapy (VMAT) plan. Methods and materials: Dose distributions of 10 prostate VMAT plans were acquired using calculation grid sizes of 1–5 mm. Dose-volume histogram (DVH) analysis was carried out to determine the dose-volume variation corresponding to the grid size change using the Gaussian error function (GEF). At the same time, dose-volume points, dose-volume parameters and radiobiological parameters were calculated based on DVHs of targets and organs at risk (OARs) for each grid size. Results: Comparing percentage variations of GEF parameters between the planning target volume (PTV) and clinical target volume (CTV), GEF parameters of the PTV were found varied more significantly than the CTV. This resulted in larger variations of dose-volume (%ΔCI=40·02 versus 13·55%, %ΔHI=12·45 versus 2·93% and %ΔGI=0·22 versus 0·06%) and radiobiological parameters (%ΔTCP=0·61 versus 0·25% and %ΔEUD=2·11 versus 0·26%) of the PTV compared with CTV. For OARs, the rectal wall showed a larger dose-volume variation than the rectum. However, similar dose-volume variation due to grid size change was not found in the bladder, bladder wall and femur. Conclusions: Knowing the dosimetric variation in this study is important to the radiotherapy staff in the quality assurance for the prostate VMAT planning. pubtype: Academic Journal doctype: equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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