Dual tracer tau PET imaging reveals different molecular targets for 11C-THK5351 and 11C-PBB3 in the Alzheimer brain.

Purpose: Several tau PET tracers have been developed, but it remains unclear whether they bind to the same molecular target on the heterogeneous tau pathology. In this study we evaluated the binding of two chemically different tau-specific PET tracers (11C-THK5351 and 11C-PBB3) in a head-to-head, in...

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Bibliographic Details

Published in:	European Journal of Nuclear Medicine & Molecular Imaging Vol. 45; no. 9; pp. 1605 - 1618
Main Authors:	Chiotis, Konstantinos, Stenkrona, Per, Almkvist, Ove, Stepanov, Vladimir, Ferreira, Daniel, Arakawa, Ryosuke, Takano, Akihiro, Westman, Eric, Varrone, Andrea, Okamura, Nobuyuki, Shimada, Hitoshi, Higuchi, Makoto, Halldin, Christer, Nordberg, Agneta
Format:	Journal Article
Published:	Springer Nature Jul2018
Online Access:	View this record in EBSCOhost