Cerebellar pilocytic astrocytoma in childhood: Investigating the long-term impact of surgery on cognitive performance and functional outcome.

Objective: Previous studies differ regarding the long-term effects of surgically removed pediatric cerebellar pilocytic astrocytomas (CPA). Thus, the aim of this study was to investigate the long-term impact on neurocognitive and functional outcome and to analyze age as an influencing factor. Method...

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Publicado en:Developmental Neurorehabilitation Vol. 21; no. 6; pp. 415 - 423
Autores principales: Pletschko, Thomas, Felnhofer, Anna, Lamplmair, Doris, Dorfer, Christian, Czech, Thomas, Chocholous, Monika, Slavc, Irene, Leiss, Ulrike
Formato: research tables/charts Journal Article
Publicado: Taylor & Francis Ltd Aug2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2018
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      pub: Taylor & Francis Ltd
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        10.1080/17518423.2017.1370502
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        atl: Cerebellar pilocytic astrocytoma in childhood: Investigating the long-term impact of surgery on cognitive performance and functional outcome.
      aug:
        au:
          Pletschko, Thomas
          Felnhofer, Anna
          Lamplmair, Doris
          Dorfer, Christian
          Czech, Thomas
          Chocholous, Monika
          Slavc, Irene
          Leiss, Ulrike
        affil: Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Wien, Austria
      sug:
        subj:
          Glioma Diagnosis
          Cognition
          Glioma Surgery
          Human
          Cerebellar Diseases
          Functional Assessment
          Pediatrics
          Quality of Health Care
          Age Factors
          Academic Achievement
          Neurophysiology
          Brain Neoplasms Diagnosis
      ab: Objective: Previous studies differ regarding the long-term effects of surgically removed pediatric cerebellar pilocytic astrocytomas (CPA). Thus, the aim of this study was to investigate the long-term impact on neurocognitive and functional outcome and to analyze age as an influencing factor. Methods: Fourteen CPA patients were compared to the age norm and to a group of 14 high-achieving peers regarding cognitive functioning, health-related quality of life (HRQoL), and stress regulation. Mean follow-up time after diagnosis was 13.29 years (range: 3-21 years). Results: Patients showed satisfactory academic achievement and did not differ from the norm except for the bodily dimension of HRQoL. However, there were marked differences in specific neurocognitive functions between patients and high achievers. Age at diagnosis did not influence neurocognitive outcome. Conclusion: CPA patients treated with surgery only seem to have a favorable long-term outcome, yet, in comparison with high achievers specific cognitive impairments become apparent.
      pubtype: Academic Journal
      doctype:
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      ougenre: Article
    language: English
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