An exudate detection method for diagnosis risk of diabetic macular edema in retinal images using feature-based and supervised classification.

The present paper aims at presenting the methodology and first results of a detection system of risk of diabetic macular edema (DME) in fundus images. The system is based on the detection of retinal exudates (Ex), whose presence in the image is clinically used for an early diagnosis of the disease....

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Publicado en:Medical & Biological Engineering & Computing Vol. 56; no. 8; pp. 1379 - 1391
Autores principales: Marin, D., Gegundez-Arias, M. E., Ponte, B., Alvarez, F., Garrido, J., Ortega, C., Vasallo, M. J., Bravo, J. M.
Formato: Journal Article
Publicado: Springer Nature Aug2018
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        10.1007/s11517-017-1771-2
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        atl: An exudate detection method for diagnosis risk of diabetic macular edema in retinal images using feature-based and supervised classification.
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        au:
          Marin, D.
          Gegundez-Arias, M. E.
          Ponte, B.
          Alvarez, F.
          Garrido, J.
          Ortega, C.
          Vasallo, M. J.
          Bravo, J. M.
        affil: Department of Electronic, Computer Science and Automatic Engineering, University of Huelva, Huelva, Spain
      sug:
        subj:
          Macular Degeneration Diagnosis
          Image Processing, Computer Assisted
          Algorithms
          Diabetic Retinopathy Diagnosis
          Exudates and Transudates
          ROC Curve
          Sensitivity and Specificity
          Automation
          Risk Factors
          Arthritis Impact Measurement Scales
          Scales
      ab: The present paper aims at presenting the methodology and first results of a detection system of risk of diabetic macular edema (DME) in fundus images. The system is based on the detection of retinal exudates (Ex), whose presence in the image is clinically used for an early diagnosis of the disease. To do so, the system applies digital image processing algorithms to the retinal image in order to obtain a set of candidate regions to be Ex, which are validated by means of feature extraction and supervised classification techniques. The diagnoses provided by the system on 1058 retinographies of 529 diabetic patients at risk of having DME show that the system can operate at a level of sensitivity comparable to that of ophthalmological specialists: it achieved 0.9000 sensitivity per patient against 0.7733, 0.9133 and 0.9000 of several specialists, where the false negatives were mild clinical cases of the disease. In addition, the level of specificity reached by the system was 0.6939, high enough to screen about 70% of the patients with no evidence of DME. These values show that the system fulfils the requirements for its possible integration into a complete diabetic retinopathy pre-screening tool for the automated management of patients within a screening programme. Graphical Abstract Diagnosis system of risk of diabetic macular edema (DME) based on exudate (Ex) detection in fundus images.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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