Foveal avascular zone and vessel density in healthy subjects: An optical coherence tomography angiography study.

Purpose: To report the normal characteristics and correlations of the foveal microvascular networks using optical coherence tomography angiography (OCTA) in a healthy Iranian population. Methods: Enface 3x3 OCTA images were obtained using the RTVue Avanti spectral-domain optical coherence tomography...

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Publicado en:Journal of Ophthalmic & Vision Research Vol. 13; no. 3; pp. 260 - 266
Autores principales: Falavarjani, Khalil, Shenazandi, Hamideh, Naseri, Dariush, Anvari, Pasha, Kazemi, Pegah, Aghamohammadi, Farzaneh, Alissmail, Feras, Alemzadeh, Sayyed
Formato: diagnostic images research tables/charts Journal Article
Publicado: Knowledge E DMCC Jul-Sep2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul-Sep2018
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        atl: Foveal avascular zone and vessel density in healthy subjects: An optical coherence tomography angiography study.
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        au:
          Falavarjani, Khalil
          Shenazandi, Hamideh
          Naseri, Dariush
          Anvari, Pasha
          Kazemi, Pegah
          Aghamohammadi, Farzaneh
          Alissmail, Feras
          Alemzadeh, Sayyed
        affil: Eye Research Center and Department of Ophthalmology, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran
      sug:
        subj:
          Tomography, Optical Coherence Methods
          Angiography
          Retina Anatomy and Histology
          Retina Blood Supply
          Retina Radiography
          Human
          Iran
          Software
          Child
          Adolescence
          Young Adult
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Age Factors
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
      ab: Purpose: To report the normal characteristics and correlations of the foveal microvascular networks using optical coherence tomography angiography (OCTA) in a healthy Iranian population. Methods: Enface 3x3 OCTA images were obtained using the RTVue Avanti spectral-domain optical coherence tomography with AngioVue software (Optovue, Fremont, CA, USA). Foveal avascular zone (FAZ) area, central foveal point thickness and inner retinal thickness at the foveal center and the vascular density of the superficial retinal capillary plexus (SCP) and deep retinal capillary plexus (DCP) in the fovea were recorded. Results: Seventy normal eyes of 70 subjects (range, 9 to 71 years) were studied. Mean FAZ area was 0.32 ± 0.11 (range, 0.13-0.67) mm2 in SCP and 0.50 ± 0.13 (range, 0.19-0.94) mm2 in DCP. Mean SCP vessel density was 29.6 ± 4.7 (range, 16.3-40.3) % in the fovea. Mean DCP vessel density was 27.0 ± 5.9 (range, 15.0-45.2) % in the fovea. The FAZ area at SCP level was negatively correlated to the central subfield thickness (P < 0.001). The FAZ area at DCP level correlated negatively to the central subfield thickness and was significantly associated to age (both P < 0.001). The foveal SCP vessel density significantly correlated with foveal thickness and the foveal DCP vessel density correlated significantly with central foveal subfield thickness and was inversely related to age (all P < 0.05). Conclusion: In this study, central foveal subfield thickness was a major determinant of the FAZ size and foveal vessel density. Age was a determinant for FAZ area and whole image vessel density in DCP.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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