Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions.
Aim. We assessed the impact of cerebral white matter lesions (WMLs) on lower urinary tract symptoms in subjects with normal neurological and cognitive function. Methods. A cohort of community-dwelling subjects aged ≥65 years were recruited to undergo MRI brain assessment. WMLs were graded using the...
| Publicado en: | Journal of Aging Research pp. 1 - 6 |
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| Autores principales: | , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
7/30/2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=130978914&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 130978914 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 20902204 B6D6 jtl: Journal of Aging Research issn: 20902204 maglogo: N pubinfo: dt: 7/30/2018 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 130978914 130978914 130978914 10.1155/2018/1582092 130978914 ppf: 1 ppct: 5 formats: tig: atl: Lower Urinary Tract Symptoms in Subjects with Subclinical Cerebral White Matter Lesions. aug: au: Yee, Chi-Hang Leung, Ching Wong, Yuki Yu-Ting Lee, Sylvia Li, Jenny Kwan, Pauline Chu, Winnie Chiu-Wing Mok, Vincent Chung-Tong Ng, Chi-Fai affil: Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong sug: subj: White Matter Pathology Brain Diseases Complications Overactive Bladder Diagnosis Cognition Human Community Living Aged Aged, 80 and Over Magnetic Resonance Imaging Diagnosis, Brain Methods Interviews Questionnaires Logistic Regression Age Factors Correlation Coefficient Multiple Logistic Regression Odds Ratio Confidence Intervals Aged: 65+ years Aged, 80 & over ab: Aim. We assessed the impact of cerebral white matter lesions (WMLs) on lower urinary tract symptoms in subjects with normal neurological and cognitive function. Methods. A cohort of community-dwelling subjects aged ≥65 years were recruited to undergo MRI brain assessment. WMLs were graded using the Fazekas scale from 0 to 3. A separate telephone interview was carried out to assess the urinary symptoms in these subjects using the questionnaire Overactive Bladder-Validated 8-Question Awareness Tool (OAB-V8). Results. 800 community-dwelling elderly subjects were recruited to undergo MRI brain. In this cohort, 431 subjects responded to the telephone interview concerning their urinary symptoms. Among the respondents, 21.1% did not exhibit any WML on their MRI brain. Most of the subjects (52.6%) exhibited grade 1 WML. On logistic regression, age was found to be positively correlated with the Fazekas score (correlation coefficient 0.203, p≤0.01). Using a cutoff of 8 on OAB-V8, 22% of the respondents experienced OAB. Presence of WML, hypertension, or diabetes mellitus was not found to be correlated with storage urinary symptoms or OAB-V8 total score. Multiple logistic regression analysis did not show the presence of WML to be associated with the diagnosis of OAB (adjusted OR 1.13, 95% CI 0.65–1.96, p=0.659). Conclusions. WML is associated with age and is common in the elderly population. Mild WML is subclinical, with no obvious neurological and urinary symptoms. Our cohort did not demonstrate a relationship between WML and lower urinary tract symptoms. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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