Classification of ADHD with bi-objective optimization.

Attention Deficit Hyperactive Disorder (ADHD) is one of the most common diseases in school aged children. In this paper, we consider using fMRI data with classification techniques to aid the diagnosis of ADHD and propose a bi-objective ADHD classification scheme based on L1-norm support vector machi...

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Publicado en:Journal of Biomedical Informatics Vol. 84; pp. 164 - 171
Autores principales: Shao, Lizhen, Xu, Yadong, Fu, Dongmei
Formato: research Journal Article
Publicado: Academic Press Inc. Aug2018
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2018
      vid: 84
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      pub: Academic Press Inc.
      place: Burlington, Massachusetts
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        atl: Classification of ADHD with bi-objective optimization.
      aug:
        au:
          Shao, Lizhen
          Xu, Yadong
          Fu, Dongmei
        affil: School of Automation and Electrical Engineering, University of Science and Technology Beijing, Beijing, China
      sug:
        subj:
          Attention Deficit Hyperactivity Disorder
          Medical Informatics Methods
          Magnetic Resonance Imaging
          Decision Making
          Attention Deficit Hyperactivity Disorder Classification
          Image Processing, Computer Assisted
          Algorithms
          Reproducibility of Results
          Brain Mapping
          Child
          Models, Statistical
          Human
          Resource Databases
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Barthel Index
          Dyadic Adjustment Scale
          Child: 6-12 years
      ab: Attention Deficit Hyperactive Disorder (ADHD) is one of the most common diseases in school aged children. In this paper, we consider using fMRI data with classification techniques to aid the diagnosis of ADHD and propose a bi-objective ADHD classification scheme based on L1-norm support vector machine (SVM). In our classification model, two objectives, namely, the margin of separation and the empirical error are considered at the same time. Then the normal boundary intersection (NBI) method of Das and Dennis is used to solve the bi-objective optimization problem. A representative nondominated set which reflects the entire trade-off information between the two objectives is obtained. Each representative nondominated point in the set corresponds to an efficient classifier. Finally a decision maker can choose a final efficient classifier from the set according to the performance of each classifier. Our scheme avoids the trial and error process for regularization hyper-parameter selection. Experimental results show that our bi-objective optimization classification scheme for ADHD diagnosis performs considerably better than some traditional classification methods.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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