Cover Image
QR Code

Sociodemographic factors, prescription history and opioid overdose deaths: a statewide analysis using linked PDMP and mortality data.

Background: Opioid overdose deaths have continued to rise in Tennessee (TN) with fentanyl emerging as a major contributor. Current data are needed to identify at-risk populations to guide prevention strategies. We conducted a large statewide observational study among TN adult decedents (2013-2016) t...

Full description

Published in:Drug & Alcohol Dependence Vol. 190; pp. 62 - 72
Main Authors: Nechuta, Sarah J., Tyndall, Benjamin D., Mukhopadhyay, Sutapa, McPheeters, Melissa L.
Format: research Journal Article
Published: Elsevier B.V. Sep2018
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131070653&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 131070653
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        03768716
        3S6
      jtl: Drug & Alcohol Dependence
      issn: 03768716
      maglogo: N
    pubinfo:
      dt: Sep2018
      vid: 190
      pid: 1004
      pub: Elsevier B.V.
    artinfo:
      ui:
        131070653
        131070653
        NLM29981943
        131070653
        10.1016/j.drugalcdep.2018.05.004
        NLM29981943
        131070653
      ppf: 62
      ppct: 10
      formats:
      tig:
        atl: Sociodemographic factors, prescription history and opioid overdose deaths: a statewide analysis using linked PDMP and mortality data.
      aug:
        au:
          Nechuta, Sarah J.
          Tyndall, Benjamin D.
          Mukhopadhyay, Sutapa
          McPheeters, Melissa L.
        affil: Tennessee Department of Health, Office of Informatics and Analytics, 665 Mainstream Drive, Nashville, TN, 37243, United States
      sug:
        subj:
          Analgesics, Opioid
          Prescriptions, Drug
          Overdose Mortality
          Data Analysis, Statistical
          Substance Abuse Detection Methods
          Overdose Economics
          Antianxiety Agents, Benzodiazepine
          Aged
          Young Adult
          Adolescence
          Mortality Trends
          Ethnic Groups
          Adult
          Human
          Fentanyl
          Overdose Diagnosis
          Male
          Socioeconomic Factors
          Female
          Middle Age
          Death Certificates
          Tennessee
          Risk Factors
          Heroin
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Aged: 65+ years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: Opioid overdose deaths have continued to rise in Tennessee (TN) with fentanyl emerging as a major contributor. Current data are needed to identify at-risk populations to guide prevention strategies. We conducted a large statewide observational study among TN adult decedents (2013-2016) to evaluate the association of sociodemographic factors and prescribing patterns with opioid overdose deaths.Methods: Among drug overdose decedents identified using death certificate data (n = 5483), we used logistic regression to estimate adjusted odds ratios and 95% confidence intervals for characteristics associated with prescription opioid (PO) (excluding fentanyl), fentanyl, and heroin alone overdoses. Among decedents linked to TN's Prescription Drug Monitoring Database using deterministic algorithms, we obtained prescription history in the year before death (n = 3971), which was evaluated by type of overdose using descriptive statistics.Results: Younger, non-White decedents had lower odds of PO overdose, while females and benzodiazepines as a contributing cause were associated with increased odds of PO overdose. Younger age, Non-Hispanic Black race/ethnicity, greater than high school education, and cocaine/other stimulants as a contributing cause were associated with increased odds of fentanyl or heroin overdoses. Over 55% of PO, 39.2% of fentanyl, and 20.7% of heroin overdoses had an active opioid prescription at death. For PO, fentanyl, and heroin decedents, respectively, 46.0%, 30.5%, and 26.2% had an active prescription for benzodiazepines at death.Conclusions: Prescription opioid overdose deaths were associated with different sociodemographic profiles and prescribing history compared to fentanyl and heroin overdose deaths in TN. Data can guide prevention strategies to reduce opioid overdose mortality.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N