Facial nerve tractography: A new tool for the detection of perineural spread in parotid cancers.
Objectives: To determine whether facial nerve MR tractography is useful in detecting PeriNeural Spread in parotid cancers.Methods: Forty-five participants were enrolled. Thirty patients with surgically managed parotid tumors (15 malignant, 15 benign) were compared with 15 healthy volunteers. All of...
| Publicado en: | European Radiology Vol. 28; no. 9; pp. 3861 - 3872 |
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| Autores principales: | , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Sep2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131115206&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131115206 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Sep2018 vid: 28 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 131115206 131115206 NLM29633003 10.1007/s00330-018-5318-1 NLM29633003 131115206 ppf: 3861 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Facial nerve tractography: A new tool for the detection of perineural spread in parotid cancers. aug: au: Rouchy, René-Charles Attyé, Arnaud Medici, Maud Renard, Félix Kastler, Adrian Grand, Sylvie Tropres, Irène Righini, Christian Adrien Krainik, Alexandre affil: Department of Neuroradiology and MRI, Grenoble Alpes University Hospital - SFR RMN Neurosciences, F-38043, Grenoble, Cedex 9, France sug: subj: Magnetic Resonance Imaging Facial Nerve Pathology Facial Nerve Parotid Neoplasms Parotid Neoplasms Pathology Male Adult Middle Age Aged Female Neoplasm Invasiveness Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objectives: To determine whether facial nerve MR tractography is useful in detecting PeriNeural Spread in parotid cancers.Methods: Forty-five participants were enrolled. Thirty patients with surgically managed parotid tumors (15 malignant, 15 benign) were compared with 15 healthy volunteers. All of them had undergone 3T-MRI with diffusion acquisition and post-processing constrained spherical deconvolution-based tractography. Parameters of diffusion-weighted sequences were b-value 1,000 s/mm2, 32 directions. Two radiologists performed a blinded visual reading of tractographic maps and graded the facial nerve average pathlength and fractional anisotropy (FA). We also compared diagnostic accuracy of tractography with morphological MRI sequences to detect PeriNeural Spread. Non-parametric methods were used.Results: Average pathlength was significantly higher in cases with PeriNeural Spread (39.86 mm [Quartile1: 36.27; Quartile3: 51.19]) versus cases without (16.23 mm [12.90; 24.90]), p<0.001. The threshold above which there was a significant association with PeriNeural Spread was set at 27.36 mm (Se: 100%; Sp: 84%; AUC: 0.96, 95% CI 0.904-1). There were no significant differences in FA between groups. Tractography map visual analyses directly displayed PeriNeural Spread in distal neural ramifications with sensitivity of 75%, versus 50% using morphological sequences.Conclusions: Tractography could be used to identify facial nerve PeriNeural Spread by parotid cancers.Key Points: • Tractography could detect facial nerve PeriNeural Spread in parotid cancers. • The average pathlength parameter is increased in case of PeriNeural Spread. • Tractography could map PeriNeural Spread more precisely than conventional imaging. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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