Multiplexed microarrays based on optically encoded microbeads.
In recent years, there has been growing interest in optically-encoded or tagged functionalized microbeads as a solid support platform to capture proteins or nucleotides which may serve as biomarkers of various diseases. Multiplexing technologies (suspension array or planar array) based on optically...
| Publicado en: | Biomedical Microdevices Vol. 20; no. 3; pp. 1 - 2 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Sep2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131169364&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131169364 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13872176 ODN jtl: Biomedical Microdevices issn: 13872176 maglogo: N pubinfo: dt: Sep2018 vid: 20 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 131169364 10.1007/s10544-018-0314-4 131169364 ppf: 1 ppct: 1 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Multiplexed microarrays based on optically encoded microbeads. aug: au: Vafajoo, Atieh Rostami, Azin Foroutan Parsa, Sanam Salarian, Reza Rabiee, Navid Rabiee, Ghazal Rabiee, Mohammad Tahriri, Mohammadreza Vashaee, Daryoosh Tayebi, Lobat Hamblin, Michael R. affil: Biomaterials Group, Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran sug: ab: In recent years, there has been growing interest in optically-encoded or tagged functionalized microbeads as a solid support platform to capture proteins or nucleotides which may serve as biomarkers of various diseases. Multiplexing technologies (suspension array or planar array) based on optically encoded microspheres have made possible the observation of relatively minor changes in biomarkers related to specific diseases. The ability to identify these changes at an early stage may allow the diagnosis of serious diseases (e.g. cancer) at a time-point when curative treatment may still be possible. As the overall accuracy of current diagnostic methods for some diseases is often disappointing, multiplexed assays based on optically encoded microbeads could play an important role to detect biomarkers of diseases in a non-invasive and accurate manner. However, detection systems based on functionalized encoded microbeads are still an emerging technology, and more research needs to be done in the future. This review paper is a preliminary attempt to summarize the state-of-the-art concerning diagnostic microbeads; including microsphere composition, synthesis, encoding technology, detection systems, and applications. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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