Pharmacokinetics and pharmacodynamics of ticagrelor in subjects on hemodialysis and subjects with normal renal function.

Purpose: This single-dose, randomized, open-label, parallel-group, and crossover study assessed pharmacokinetics (PK), pharmacodynamics (PD), and safety of ticagrelor in subjects on hemodialysis versus healthy subjects.Methods: Hemodialysis subjects were randomized, receiving a single ticagrelor 90-...

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Bibliographic Details

Published in:	European Journal of Clinical Pharmacology Vol. 74; no. 9; pp. 1141 - 1149
Main Authors:	Teng, Renli, Muldowney, Sharen, Zhao, Yonggang, Berg, Jolene Kay, Lu, Jonathan, Khan, Naeem D.
Format:	research tables/charts randomized controlled trial Journal Article
Published:	Springer Nature Sep2018
Online Access:	View this record in EBSCOhost