Is PASH Syndrome a Biofilm Disease?: A Case Series and Review of the Literature.

Introduction. When occurring together, pyoderma gangrenosum, severe acne, and hidradenitis suppurativa have been described as PASH syndrome. Due to the chronic autoinflammatory state existing in affected patients, PASH syndrome has been attributed to the dysregulation of wound healing. Case Reports....

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Publicado en:Wounds: A Compendium of Clinical Research & Practice Vol. 30; no. 8; pp. 216 - 229
Autores principales: Ead, Joey Karim, Snyder, Robert J., Wise, Jaime, Cuffy, Cherison, Jafary, Hamed, Fischborn, Karen
Formato: case study pictorial tables/charts Journal Article
Publicado: HMP Global Aug2018
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Is PASH Syndrome a Biofilm Disease?: A Case Series and Review of the Literature.
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          Ead, Joey Karim
          Snyder, Robert J.
          Wise, Jaime
          Cuffy, Cherison
          Jafary, Hamed
          Fischborn, Karen
        affil: Barry University School of Podiatric Medicine, Miami Shores, FL
      sug:
        subj:
          Pyoderma Gangrenosum Symptoms
          Acne Vulgaris Symptoms
          Hidradenitis Suppurativa Symptoms
          Biofilms
          Pyoderma Gangrenosum Microbiology
          Acne Vulgaris Microbiology
          Hidradenitis Suppurativa Microbiology
          Female
          Adult
          Wound Healing
          Adult: 19-44 years
          Female
      ab: Introduction. When occurring together, pyoderma gangrenosum, severe acne, and hidradenitis suppurativa have been described as PASH syndrome. Due to the chronic autoinflammatory state existing in affected patients, PASH syndrome has been attributed to the dysregulation of wound healing. Case Reports. Two cases are presented that demonstrate the paradigmatic clinical features of PASH syndrome and its potential link as an expanding spectrum of bacterial biofilm disorder. Conclusions. As reported herein, based on biofilm's clinical presentation and resistance to proper wound healing, it could serve as the common denominator and may redirect clinicians' treatment pathways in the near future.
      pubtype: Periodical
      doctype:
        case study
        pictorial
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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