Imaging appearance of well-differentiated liposarcomas with myxoid stroma.
Objective: Describe the imaging appearance of well-differentiated liposarcoma with myxoid stroma (WDLMS) and correlate with histopathology.Materials and Methods: A keyword search of the institution medical records was performed from 1 January 2000 to 30 June 2017. The histopathology slides of cases...
| Publicado en: | Skeletal Radiology Vol. 47; no. 10; pp. 1371 - 1383 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131319834&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131319834 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03642348 O14 jtl: Skeletal Radiology issn: 03642348 maglogo: N pubinfo: dt: Oct2018 vid: 47 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 131319834 131319834 NLM29663025 10.1007/s00256-018-2940-6 NLM29663025 131319834 ppf: 1371 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Imaging appearance of well-differentiated liposarcomas with myxoid stroma. aug: au: Morag, Yoav Yablon, Corrie Brigido, Monica Kalume Jacobson, Jon Lucas, David affil: Department of Radiology, University of Michigan Hospitals, Taubman Center 2910F, SPC 5326, 1500 East Medical Center Drive, 48109-5326, Ann Arbor, MI, USA sug: subj: Muscle Neoplasms Retroperitoneal Neoplasms Liposarcoma Thigh Magnetic Resonance Imaging Retroperitoneal Neoplasms Pathology Middle Age Liposarcoma Pathology Ultrasonography Tomography, X-Ray Computed Aged Male Adult Lipoma Tibia Aged, 80 and Over Muscle Neoplasms Pathology Female Barthel Index Middle Aged: 45-64 years Aged: 65+ years Adult: 19-44 years Aged, 80 & over Male Female ab: Objective: Describe the imaging appearance of well-differentiated liposarcoma with myxoid stroma (WDLMS) and correlate with histopathology.Materials and Methods: A keyword search of the institution medical records was performed from 1 January 2000 to 30 June 2017. The histopathology slides of cases identified in this fashion were then reviewed by a pathologist. Additional cases were prospectively collected from extramural referrals and tumor boards. Diagnostic imaging studies of pathologically proven cases of WDLMS were then reviewed in consensus and correlated with pathology.Results: Ten cases of pathologically proven WDLMS were identified (7 men, 3 women, ages 26-81). Tumor location included the retroperitoneum (n = 5), thigh (n = 4), and the shin (n = 1). Nine patients had macroscopic fat on imaging. The nonlipomatous components had a variable appearance, including septal, nodular, and lacelike patterns. Two cases included two distinct areas that were predominantly myxoid or lipomatous ("bi-morphic"). One tumor had no macroscopic fat on imaging. On CT, the nonlipomatous nodular components were hypodense/had hypodense areas. On MRI, the nodular components had intermediate/bright T2W signal. Interval nonlipomatous nodular growth was identified in 3 cases.Conclusion: WDLMS may present on imaging as a mass with variable morphology and amounts of nonlipomatous components. Histopathological diagnosis of WDLMS is challenging and imaging correlation may be helpful, as this tumor may have ≥50% fatty volume, may have a myxoid nodular component or bi-morphic appearance, or may be located in the retroperitoneum, features that are unusual for myxoid liposarcoma. WDLMS with a nodular component cannot be distinguished from dedifferentiated liposarcoma based on imaging alone. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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