Quantification of fat content in lipid-rich myxoid liposarcomas with MRI: a single-center experience with survival analysis.
Objective: To determine the fat content of myxoid liposarcomas (MLS) on MRI and to identify any association between lipid content and survival.Materials and Methods: The fat percentage of MLS diagnosed between January 2006 and December 2016 at a single institution was assessed by two radiologists on...
| Publicado en: | Skeletal Radiology Vol. 47; no. 10; pp. 1411 - 1418 |
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| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Oct2018
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131319844&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131319844 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03642348 O14 jtl: Skeletal Radiology issn: 03642348 maglogo: N pubinfo: dt: Oct2018 vid: 47 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 131319844 131319844 NLM29948035 10.1007/s00256-018-2974-9 NLM29948035 131319844 ppf: 1411 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Quantification of fat content in lipid-rich myxoid liposarcomas with MRI: a single-center experience with survival analysis. aug: au: Kuyumcu, Gokhan Rubin, Brian P. Bullen, Jennifer Ilaslan, Hakan affil: Imaging Institute, Cleveland Clinic, 9500 Euclid Avenue, 44195, Cleveland, OH, USA sug: subj: Magnetic Resonance Imaging Liposarcoma, Myxoid Neoplasms, Adipose Tissue Liposarcoma, Myxoid Mortality Survival Analysis Cox Proportional Hazards Model Retrospective Design Neoplasms, Adipose Tissue Mortality Kaplan-Meier Estimator Lipids ab: Objective: To determine the fat content of myxoid liposarcomas (MLS) on MRI and to identify any association between lipid content and survival.Materials and Methods: The fat percentage of MLS diagnosed between January 2006 and December 2016 at a single institution was assessed by two radiologists on preoperative MR images. A Cox proportional hazard model was used to determine any association between tumor fat percentage and survival time. Tumor fat percentage was the single predictor in the model. A significance level of 0.05 was used. The Kaplan-Meier estimator was also used to provide a nonparametric estimate of the survivor function within the entire sample and within two patient subgroups consists of lipid-rich and lipid-poor tumors. Lipid-rich tumors were defined as any tumors showing more than 20% of fat on MRI. A 20% cutoff was determined arbitrarily.Results: Of the 43 cases identified through retrospective review, 8 tumors demonstrated ≥10% fat on MRI, and 4 tumors demonstrated ≥20% fat (highest fat percentage, 38%). There was no significant survival difference between patients with high tumor fat, which was defined as ≥20% fat, compared with those with little to no tumor fat.Conclusion: Myxoid liposarcomas may demonstrate a higher fat content on MRI than has previously been reported in the literature. Increased tumor fat percentage in lipid-rich tumors was not found to be associated with increased risk of death. Radiologists must be aware of the existence of MLS lesions with higher fat content. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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