Bestrahlungsplanung für Wirbelsäulen-Radiochirurgie : Eine kompetitive Multiplattform-Benchmark-Studie.
Purpose: To investigate the quality of treatment plans of spinal radiosurgery derived from different planning and delivery systems. The comparisons include robotic delivery and intensity modulated arc therapy (IMAT) approaches. Multiple centers with equal systems were used to reduce a bias based on...
| Publicado en: | Strahlentherapie und Onkologie Vol. 194; no. 9; pp. 843 - 855 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Sep2018
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=131372863&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 131372863 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01797158 NZE jtl: Strahlentherapie und Onkologie issn: 01797158 maglogo: N pubinfo: dt: Sep2018 vid: 194 iid: 9 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 131372863 131372863 NLM29802435 131372863 10.1007/s00066-018-1314-2 NLM29802435 131372863 ppf: 843 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Bestrahlungsplanung für Wirbelsäulen-Radiochirurgie : Eine kompetitive Multiplattform-Benchmark-Studie. aug: au: Moustakis, Christos Chan, Mark K. H. Kim, Jinkoo Nilsson, Joakim Bergman, Alanah Bichay, Tewfik J. Palazon Cano, Isabel Cilla, Savino Deodato, Francesco Doro, Raffaela Dunst, Jürgen Eich, Hans Theodor Fau, Pierre Fong, Ming Haverkamp, Uwe Heinze, Simon Hildebrandt, Guido Imhoff, Detlef de Klerck, Erik Köhn, Janett affil: Department of Radiation Oncology, University Hospital Münster, Albert-Schweitzer-Campus 1, Gebäude A1, 48149, Münster, Germany sug: subj: Radiosurgery Methods Spinal Neoplasms Radiotherapy Benchmarking Spinal Neoplasms Thoracic Vertebrae Surgery Radiotherapy, Computer-Assisted Methods Radiotherapy, Conformal Methods Radiotherapy, Conformal Equipment and Supplies Body Regions Aged Radiosurgery Equipment and Supplies Robotic Surgical Procedures Equipment and Supplies Radiation Dosage Neoplasm Recurrence, Local Radiotherapy Human Algorithms Validation Studies Comparative Studies Evaluation Research Multicenter Studies Ferrans and Powers Quality of Life Index Aged: 65+ years ab: Purpose: To investigate the quality of treatment plans of spinal radiosurgery derived from different planning and delivery systems. The comparisons include robotic delivery and intensity modulated arc therapy (IMAT) approaches. Multiple centers with equal systems were used to reduce a bias based on individual's planning abilities. The study used a series of three complex spine lesions to maximize the difference in plan quality among the various approaches.Methods: Internationally recognized experts in the field of treatment planning and spinal radiosurgery from 12 centers with various treatment planning systems participated. For a complex spinal lesion, the results were compared against a previously published benchmark plan derived for CyberKnife radiosurgery (CKRS) using circular cones only. For two additional cases, one with multiple small lesions infiltrating three vertebrae and a single vertebra lesion treated with integrated boost, the results were compared against a benchmark plan generated using a best practice guideline for CKRS. All plans were rated based on a previously established ranking system.Results: All 12 centers could reach equality (n = 4) or outperform (n = 8) the benchmark plan. For the multiple lesions and the single vertebra lesion plan only 5 and 3 of the 12 centers, respectively, reached equality or outperformed the best practice benchmark plan. However, the absolute differences in target and critical structure dosimetry were small and strongly planner-dependent rather than system-dependent. Overall, gantry-based IMAT with simple planning techniques (two coplanar arcs) produced faster treatments and significantly outperformed static gantry intensity modulated radiation therapy (IMRT) and multileaf collimator (MLC) or non-MLC CKRS treatment plan quality regardless of the system (mean rank out of 4 was 1.2 vs. 3.1, p = 0.002).Conclusions: High plan quality for complex spinal radiosurgery was achieved among all systems and all participating centers in this planning challenge. This study concludes that simple IMAT techniques can generate significantly better plan quality compared to previous established CKRS benchmarks. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|